A forum to discuss research on the origins of MS and its development.
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miRNA dysregulation as the source of the disease
Replies: 15
by
frodo » Mon Oct 16, 2017 11:28 pm
First post
Micro-RNA ( miRNA ) has been proposed as a biomarker of axon degeneration, but some authors have proposed that they could be the source of the...
Last post
2021 Jan 16
Department of Medical Genetics, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran
Identification of...
- 15 Replies
- 2562 Views
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Last post by Petr75
Mon Jan 18, 2021 11:56 pm
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serum biomarkers: Phospholipids
by
frodo » Wed Jan 13, 2021 5:31 am
Serum phospholipidomics reveals altered lipid profile and promising biomarkers in multiple sclerosis
Conclusion
From this study, we can...
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- 45 Views
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Last post by frodo
Wed Jan 13, 2021 5:31 am
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- 45 Views
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Last post by frodo
Tue Jan 12, 2021 10:40 am
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- 46 Views
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Last post by frodo
Tue Jan 12, 2021 9:05 am
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subtyping RRMS
by
frodo » Tue Jan 05, 2021 3:00 pm
Subtyping relapsing–remitting multiple sclerosis using structural MRI
Abstract
Background and purpose
Subtyping relapsing–remitting multiple...
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- 61 Views
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Last post by frodo
Tue Jan 05, 2021 3:00 pm
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Dogs can smell MS
Replies: 3
by
frodo » Wed Dec 04, 2019 12:54 am
First post
These Dogs Know When Their Owners Are About to Have an MS Flare
Health and wellness touch everyone’s life differently. Here are some stories....
Last post
Detecting Multiple Sclerosis via breath analysis using an eNose, a pilot study
Abstract
Objective: In the present study we investigated whether...
- 3 Replies
- 613 Views
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Last post by frodo
Tue Dec 22, 2020 12:27 pm
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Herpes simplex virus
by
Petr75 » Tue Dec 22, 2020 12:07 am
2020 Nov 19
Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China
Positive...
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- 56 Views
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Last post by Petr75
Tue Dec 22, 2020 12:07 am
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Microglia in the pathogenesis of MS
Replies: 20
by
frodo » Mon Jul 23, 2018 11:13 am
First post
Microglia in the pathogenesis of MS
We postulate that the immune reaction initiates in the CNS and immune cells (including T cells/B cell)...
Last post
2020 Nov 6
Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB, Canada
Microglia Diversity in Health and Multiple...
- 20 Replies
- 3281 Views
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Last post by Petr75
Tue Dec 15, 2020 10:32 am
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MRZ Reaction in PPMS
by
frodo » Tue Dec 01, 2020 5:45 am
Cerebrospinal Fluid Biomarkers in Relation to MRZ Reaction Status in Primary Progressive Multiple Sclerosis
Abstract
The MRZ reaction (MRZR)...
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- 237 Views
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Last post by frodo
Tue Dec 01, 2020 5:45 am
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- 167 Views
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Last post by frodo
Tue Dec 01, 2020 5:37 am
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lipid metabolism and MS
by
frodo » Wed Nov 18, 2020 12:40 am
Serum phospholipidomics reveals altered lipid profile and promising biomarkers in multiple sclerosis
Abstract
Multiple sclerosis is a...
- 0 Replies
- 213 Views
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Last post by frodo
Wed Nov 18, 2020 12:40 am
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- 0 Replies
- 211 Views
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Last post by frodo
Thu Nov 12, 2020 4:04 am
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MBP in saliva as biomarker
by
frodo » Tue Nov 10, 2020 5:13 am
Serum and saliva Myelin basic protein as Multiple sclerosis biomarker
Abstract:
Objective: Multiple sclerosis (MS) is considered as motor and...
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- 181 Views
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Last post by frodo
Tue Nov 10, 2020 5:13 am
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- 198 Views
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Last post by frodo
Fri Nov 06, 2020 5:09 am
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- 183 Views
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Last post by frodo
Fri Nov 06, 2020 2:45 am
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- 198 Views
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Last post by frodo
Tue Nov 03, 2020 6:09 am
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- 0 Replies
- 210 Views
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Last post by frodo
Tue Nov 03, 2020 6:07 am
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MS biomarker in serum
by
frodo » Tue Nov 03, 2020 6:04 am
Detection of Multiple Sclerosis Biomarkers in Serum by Ganglioside Microarrays and Surface Plasmon Resonance Imaging
Abstract
Multiple...
- 0 Replies
- 184 Views
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Last post by frodo
Tue Nov 03, 2020 6:04 am
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Complex genetic signatures
by
Petr75 » Wed Oct 14, 2020 8:35 am
2020 Oct
Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Cagliari, Italy
Complex genetic signatures in immune...
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- 201 Views
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Last post by Petr75
Wed Oct 14, 2020 8:35 am
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- 0 Replies
- 338 Views
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Last post by frodo
Fri Oct 09, 2020 7:12 am
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specific CSF biomarkers review
by
frodo » Fri Oct 02, 2020 6:11 am
CSF biomarkers in multiple sclerosis: beyond neuroinflammation
making a long story short:
Diagnostic biomarkers: IgG oligoclonal bands, IgG...
- 0 Replies
- 246 Views
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Last post by frodo
Fri Oct 02, 2020 6:11 am
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lipids differentiate PPMS and SPMS
by
frodo » Fri Oct 02, 2020 4:47 am
Lipidomic UPLC-MS/MS Profiles of Normal-Appearing White Matter Differentiate Primary and Secondary Progressive Multiple Sclerosis
Abstract...
- 0 Replies
- 234 Views
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Last post by frodo
Fri Oct 02, 2020 4:47 am
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OCBs can separate MS from lyme
by
frodo » Thu Oct 01, 2020 6:44 am
Cerebrospinal fluid oligoclonal bands in Neuroborreliosis are specific for Borrelia burgdorferi
Background
Cerebrospinal fluid (CSF)...
- 0 Replies
- 261 Views
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Last post by frodo
Thu Oct 01, 2020 6:44 am
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EBNA1 (EBV protein) reactive to OCBs
by
frodo » Fri Sep 25, 2020 7:21 am
Antibodies from multiple sclerosis brain identified Epstein-Barr virus nuclear antigen 1 & 2 epitopes which are recognized by oligoclonal bands...
- 0 Replies
- 259 Views
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Last post by frodo
Fri Sep 25, 2020 7:21 am
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biomarkers review
by
frodo » Tue Sep 22, 2020 11:21 am
Development of robust targeted proteomics assays for cerebrospinal fluid biomarkers in multiple sclerosis
Background
Verification of...
- 0 Replies
- 242 Views
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Last post by frodo
Tue Sep 22, 2020 11:21 am
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Creatine metabolic alterations in MS
by
frodo » Thu Sep 17, 2020 6:55 am
Creatine and multiple sclerosis
ABSTRACT
Multiple sclerosis (MS) is a complex and debilitating neurodegenerative disease, with unknown...
- 0 Replies
- 274 Views
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Last post by frodo
Thu Sep 17, 2020 6:55 am
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Two molecular types of lesions via MRI
by
frodo » Mon Sep 14, 2020 1:34 am
Characterization of multiple sclerosis lesions with distinct clinical correlates through quantitative diffusion MRI
Highlights :
• Macroscopic...
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- 280 Views
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Last post by frodo
Mon Sep 14, 2020 1:34 am
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- 267 Views
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Last post by Petr75
Sat Sep 05, 2020 8:40 pm
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Three different biopsy patterns
by
frodo » Thu Sep 03, 2020 12:31 am
Different pathological processes for acute white matter lesions in multiple sclerosis
Abstract
Introduction :
Multiple sclerosis (MS) has...
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- 233 Views
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Last post by frodo
Thu Sep 03, 2020 12:31 am
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- 0 Replies
- 213 Views
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Last post by frodo
Tue Sep 01, 2020 5:25 am
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Reelin depletion for MS
by
jimmylegs » Sun Aug 30, 2020 10:48 am
Reelin depletion protects against autoimmune encephalomyelitis by decreasing vascular adhesion of leukocytes
...Our findings suggest Reelin...
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- 215 Views
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Last post by jimmylegs
Sun Aug 30, 2020 10:48 am
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- 0 Replies
- 218 Views
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Last post by frodo
Thu Aug 27, 2020 5:43 am
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NFL shows silent relapses in PPMS cases
by
frodo » Tue Aug 25, 2020 8:51 am
PPMS is supposed to advance in absence of relapses. Anyway, it seems than some silent relapses can be seen via NFL
CSF neurofilament light chain...
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- 229 Views
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Last post by frodo
Tue Aug 25, 2020 8:51 am
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- 216 Views
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Last post by frodo
Sun Aug 23, 2020 11:38 pm
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- 139 Views
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Last post by frodo
Thu Aug 20, 2020 11:46 pm
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Retinal damage could be due to subclinical inflammation in optic nerve
Replies: 1
by
frodo » Tue Aug 11, 2020 2:32 am
First post
Retinal and brain damage during multiple sclerosis course: inflammatory activity is a key factor in the first 5 years
The mechanisms by which...
Last post
Characterization of Retinal vascular changes in Multiple Sclerosis using Adaptive Optics and OCTA
Abstract
Purpose : Characterize...
- 1 Replies
- 264 Views
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Last post by frodo
Thu Aug 20, 2020 2:52 am
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- 0 Replies
- 142 Views
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Last post by frodo
Thu Aug 20, 2020 12:25 am
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- 149 Views
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Last post by frodo
Thu Aug 20, 2020 12:03 am
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- 134 Views
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Last post by frodo
Wed Aug 19, 2020 11:48 pm
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Biotin could make MS worse
Replies: 2
by
frodo » Tue Aug 11, 2020 2:13 am
First post
Not good news for those on Biotin, but very interesting from the point of view of the pathogenesis research.
The Rise and Fall of High-Dose Biotin...
Last post
I didn't know that. Thanks.
- 2 Replies
- 333 Views
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Last post by frodo
Wed Aug 19, 2020 5:07 am
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- 0 Replies
- 164 Views
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Last post by frodo
Wed Aug 19, 2020 4:56 am
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- 298 Views
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Last post by frodo
Mon Aug 17, 2020 2:47 am
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- 0 Replies
- 250 Views
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Last post by frodo
Mon Aug 17, 2020 12:33 am
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biomarkers for pediatric MS
by
frodo » Wed Aug 12, 2020 11:14 am
Analysis of plasma protein biomarkers in childhood onset multiple sclerosis
Highlights
• Significant proteomic differences were found between...
- 0 Replies
- 255 Views
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Last post by frodo
Wed Aug 12, 2020 11:14 am
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biomarker for response to IFNbeta
by
frodo » Wed Aug 12, 2020 10:58 am
IFI35 as a biomolecular marker of neuroinflammation and treatment response in multiple sclerosis
Highlights
• No biomarker is available for...
- 0 Replies
- 247 Views
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Last post by frodo
Wed Aug 12, 2020 10:58 am
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Metallic elements in MS
by
frodo » Wed Aug 12, 2020 12:12 am
A preliminary study of the concentration of metallic elements in the blood of patients with multiple sclerosis as measured by icp‑MS
It is...
- 0 Replies
- 222 Views
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Last post by frodo
Wed Aug 12, 2020 12:12 am
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Biomarker for the progressive phase
by
frodo » Tue Aug 11, 2020 2:06 am
Distinctive sphingolipid patterns in chronic multiple sclerosis lesions
Abstract
Multiple sclerosis (MS) is a CNS disease characterized by...
- 0 Replies
- 228 Views
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Last post by frodo
Tue Aug 11, 2020 2:06 am
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- 0 Replies
- 221 Views
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Last post by frodo
Tue Aug 11, 2020 2:03 am
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Novel blood-based biomarker for MS
by
frodo » Thu Aug 06, 2020 7:39 am
Blood platelet RNA enables the detection of multiple sclerosis
Background
In multiple sclerosis (MS), clinical assessment, MRI and...
- 0 Replies
- 236 Views
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Last post by frodo
Thu Aug 06, 2020 7:39 am
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- 0 Replies
- 262 Views
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Last post by frodo
Thu Jul 30, 2020 11:52 pm
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