Mavenclad (Cladribine)

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Mavenclad prescribing information

Last post by NHE « Thu Apr 25, 2019 3:03 pm

by NHE » Thu Apr 25, 2019 3:03 pm

Mavenclad prescribing information

0 Replies

1237 Views

Last post by NHE
Thu Apr 25, 2019 3:03 pm
cladribine / leustatin / mavenclad

Last post by NHE « Thu May 23, 2019 6:47 am
Replies: 25
by jimmylegs » Thu Oct 18, 2018 8:48 am
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First post

ok so i have this new-to-me neuro i've just seen for the second time. she's making the best attempt to date, of convincing me to consider a dmd.
for...

Last post

Hey I just got an email ad for Mavenclad (cladribine) and its apparently approved, but my doctor friend says never take a new treatment in the first...
25 Replies

7943 Views

Last post by NHE
Thu May 23, 2019 6:47 am
2019 news: FDA Approves Cladribine

Last post by jimmylegs « Thu Apr 25, 2019 1:18 pm
Replies: 1
by jimmylegs » Thu Apr 25, 2019 1:06 pm

First post

FDA Approves Cladribine -- Brand named Mavenclad® -- for People with Relapsing-Remitting MS and Active Secondary Progressive MS - UPDATE

March...

Last post

Health Canada approves oral Mavenclad™ for the management of relapsing-remitting MS (2017)

Mavenclad (cladribine) approved for use by the NHS in...

1 Replies

1611 Views

Last post by jimmylegs
Thu Apr 25, 2019 1:18 pm
2017: Health Canada approves oral Mavenclad™ for RRMS

Last post by jimmylegs « Sat Feb 09, 2019 8:26 am

by jimmylegs » Sat Feb 09, 2019 8:26 am

2+ yr-old 'news':

Health Canada approves oral Mavenclad™ for the management of relapsing-remitting MS

Health Canada has recently approved EMD...

0 Replies

1411 Views

Last post by jimmylegs
Sat Feb 09, 2019 8:26 am
Mavenclad

Last post by MySelf « Wed Mar 14, 2018 7:47 am
Replies: 2
by MySelf » Tue Mar 06, 2018 5:13 pm

First post

Hi, I'm new to this forum... wondering if anyone has experience with mavenclad?
I wasn't sure where to post this so forgive me if I'm in the wron...

Last post

I'm interested in hearing from anyone who has or is currently taking the drug. I haven't managed to find much online from actual users, only info on...

2 Replies

2622 Views

Last post by MySelf
Wed Mar 14, 2018 7:47 am
Cladribine gets approval in Scotland

Last post by MSUK « Wed Feb 14, 2018 6:11 am

by MSUK » Wed Feb 14, 2018 6:11 am

NHS Scotland has accepted cladribine (Mavenclad) as a treatment option for people with highly active multiple sclerosis (MS) living in Scotland…

0 Replies

1580 Views

Last post by MSUK
Wed Feb 14, 2018 6:11 am
Cladribine available to UK MS patients tomorrow...

Last post by jimmylegs « Thu Nov 09, 2017 10:41 am
Replies: 1
by MSUK » Thu Nov 09, 2017 7:41 am

First post

NHS England strikes deal that makes Cladribine available to MS patients tomorrow

NHS Chief, Simon Stevens has announce that NHS England has struck a...

Last post

NHS England strikes new deals to make two new innovative treatments available routinely on the NHS

NHS chief Simon Stevens will today announce...

1 Replies

1343 Views

Last post by jimmylegs
Thu Nov 09, 2017 10:41 am
European Commission grants approval for cladribine

Last post by MSUK « Tue Aug 29, 2017 4:04 am

by MSUK » Tue Aug 29, 2017 4:04 am

The European Commission has approved Mavenclad, more commonly known as cladribine, for the treatment of highly active relapsing remitting multiple...

0 Replies

1294 Views

Last post by MSUK
Tue Aug 29, 2017 4:04 am
Cladribine Tablets found to reduce brain atrophy in RRMS...

Last post by aabreu « Mon Jul 17, 2017 2:52 pm
Replies: 2
by MSUK » Wed Feb 15, 2017 6:24 am

First post

Cladribine Tablets found to reduce brain atrophy in RRMS patients

New findings from a study by Merck KGaA, Darmstaft, Germany, a science and...

Last post

I'm looking for a provider in USA that will treat patients off label it Cladribine. Can anyone help?

Thank you
AA

2 Replies

1497 Views

Last post by aabreu
Mon Jul 17, 2017 2:52 pm
Oral Cladribine tablets for MSapproved in Australia

Last post by aabreu « Mon Jul 17, 2017 2:44 pm
Replies: 1
by MSUK » Fri Sep 03, 2010 6:15 am

First post

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, announced today that the Australian Therapeutic Goods Administration (TGA) has approved...

Last post

I'm in USA. Does anyone know what the treatment costs? I would make the trip for the medication if I can afford it and I could find a doctor there...

1 Replies

2162 Views

Last post by aabreu
Mon Jul 17, 2017 2:44 pm
Is anyone taking Cladribine off label currently????

Last post by aabreu « Mon Jul 17, 2017 2:41 pm
Replies: 1
by sarah859 » Mon Feb 15, 2016 2:33 am

First post

Barts blog keeps writting heaps on Cladribine and I'm keen to hear from anyone who took it or is currenlty taking it off label. Thanks for sharing...

Last post

I am very curious about this. Does anyone know of a doctor that is treating patients with Cladribine off label?
Please help.

Thank you
AA

1 Replies

1733 Views

Last post by aabreu
Mon Jul 17, 2017 2:41 pm
Cladribine tablets receives positive CHMP opinion...

Last post by MSUK « Mon Jun 26, 2017 7:18 am

by MSUK » Mon Jun 26, 2017 7:18 am

Cladribine tablets receives positive CHMP opinion for treatment of RRMS

Science and technology company, Merck has revealed it has received a...

0 Replies

1204 Views

Last post by MSUK
Mon Jun 26, 2017 7:18 am
Cladribine tablets

Last post by NHE « Thu Jan 19, 2017 11:09 pm
Replies: 1
by Luvsadonut » Thu Jan 19, 2017 6:22 am

First post

Hi
Does anybody have any experience with Cladribine tablets? I saw a new Neuro yesterday and I think he will push for me to use these tablets. Ive...

Last post

Did you try the forum's search tool?

There are 205 results for cladribine.

1 Replies

1355 Views

Last post by NHE
Thu Jan 19, 2017 11:09 pm
Cladribine cleared for review

Last post by frodo « Fri Aug 19, 2016 7:38 am
Replies: 1
by MSUK » Mon Jul 18, 2016 3:04 am

First post

Merck, a leading science and technology company, today announced that the European Medicines Agency (EMA) has accepted for review the Marketing...

Last post

Merck, a leading science and technology company, today announced that the European Medicines Agency (EMA) has accepted for review the Marketing...

1 Replies

1313 Views

Last post by frodo
Fri Aug 19, 2016 7:38 am
Data shows Cladribine benefits persist in RRMS patients

Last post by MSUK « Tue Apr 19, 2016 4:33 am

by MSUK » Tue Apr 19, 2016 4:33 am

The effects of Cladribine for relapsing-remitting multiple sclerosis (RRMS) patients have been demonstrated to last for up to four years after...

0 Replies

1332 Views

Last post by MSUK
Tue Apr 19, 2016 4:33 am
Merck to submit Cladribine for Euro registration

Last post by MSUK « Fri Sep 11, 2015 5:48 am

by MSUK » Fri Sep 11, 2015 5:48 am

German healthcare firm Merck has announced it is to submit its investigational treatment Cladribine Tablets for the treatment of relapsing MS for...

0 Replies

1941 Views

Last post by MSUK
Fri Sep 11, 2015 5:48 am
Cladrabine - Movectro

Last post by brog64 « Sun Jun 26, 2011 3:32 pm
Replies: 64
by Becia » Mon May 30, 2011 12:44 am
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First post

Hi all,
is any one on Cladrabine, i am thinking swap from copaxone to C but need more information.please help

take care
becia

Last post

Hi Becia,

I am on Cladribine and have taken my first 5 day course. As you are probably aware Merck has with drawn the drug from the market and no...
64 Replies

14383 Views

Last post by brog64
Sun Jun 26, 2011 3:32 pm
Movectro (Cladribine) withdrawn by Merck on FDA feedback

Last post by brog64 « Sun Jun 26, 2011 3:26 pm
Replies: 4
by MSUK » Wed Jun 22, 2011 12:15 am

First post

German drugmaker Merck KGaA has given up seeking approval for its multiple sclerosis pill cladribine after U.S. drug regulators said more costly...

Last post

Hi,

I live in Australia and started on Cladribine earlier this month. I have been in touch with Merck and they are withdrawing the drug world wide...

4 Replies

4201 Views

Last post by brog64
Sun Jun 26, 2011 3:26 pm
Merck fined AUD$75,000 for Movectro advertising

Last post by hwebb « Tue Apr 19, 2011 2:55 am

by hwebb » Tue Apr 19, 2011 2:55 am

Merck Serono, makers of leukemia drug Cladribine (now marketed as MS drug Movectro) have been fined A$75,000 for breach of the Medicines Australia...

0 Replies

2422 Views

Last post by hwebb
Tue Apr 19, 2011 2:55 am
Disease-activity-free status in patients with cladribine

Last post by MSUK « Wed Mar 16, 2011 12:07 am

by MSUK » Wed Mar 16, 2011 12:07 am

Sustained disease-activity-free status in patients with relapsing-remitting multiple sclerosis treated with cladribine tablets in the CLARITY study:...

0 Replies

1934 Views

Last post by MSUK
Wed Mar 16, 2011 12:07 am
Complete response letter on Cladribine tablets issued by FDA

Last post by HarryZ « Wed Mar 02, 2011 7:37 am
Replies: 1
by MSUK » Wed Mar 02, 2011 12:48 am

First post

EMD Serono, Inc., an affiliate of Merck KGaA, Darmstadt, Germany, announced today that it received a complete response letter (CRL) from the U.S....

Last post

Sounds like the FDA is being far more cautious with the side effect issue after the fiasco of quickly approving Tysabri a few years ago.

Harry

1 Replies

2097 Views

Last post by HarryZ
Wed Mar 02, 2011 7:37 am
Merck withdraws EU license application for Movectro

Last post by MSUK « Thu Feb 17, 2011 7:12 am

by MSUK » Thu Feb 17, 2011 7:12 am

German drugmaker Merck KGA has withdrawn a European marketing authorisation application for its multiple sclerosis (MS) drug Movectro after it was...

0 Replies

2100 Views

Last post by MSUK
Thu Feb 17, 2011 7:12 am
EU drug watchdog deals another blow to Cladribine

Last post by MSUK « Fri Jan 21, 2011 12:52 am

by MSUK » Fri Jan 21, 2011 12:52 am

European regulators dealt Merck KGaA another blow by sticking with their recommendation against what once was the group's biggest pipeline hope,...

0 Replies

1732 Views

Last post by MSUK
Fri Jan 21, 2011 12:52 am
FDA extends priority review of oral MS drug Cladribine

Last post by MSUK « Fri Nov 26, 2010 2:44 am

by MSUK » Fri Nov 26, 2010 2:44 am

The U.S. drugs watchdog will take more time to decide over Merck KGaA's multiple sclerosis (MS) pill, the German company said on Friday, two months...

0 Replies

2112 Views

Last post by MSUK
Fri Nov 26, 2010 2:44 am
Enrollment complete in ORACLE MS study of cladribine tablets

Last post by MSUK « Wed Nov 17, 2010 1:25 am

by MSUK » Wed Nov 17, 2010 1:25 am

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, announced today the completion of patient enrollment in the ORACLE MS1 clinical study....

0 Replies

1957 Views

Last post by MSUK
Wed Nov 17, 2010 1:25 am
Merck KGaA to ask EU agency to reconsider MS oral drug

Last post by MSUK « Mon Oct 11, 2010 1:44 am

by MSUK » Mon Oct 11, 2010 1:44 am

German drugmaker Merck KGaA plans to ask a European watchdog to review a negative opinion issued on multiple sclerosis drug cladribine last month...

0 Replies

1705 Views

Last post by MSUK
Mon Oct 11, 2010 1:44 am
Multiple Sclerosis Treated With Cladribine Remain Progressio

Last post by scorpion « Wed Sep 29, 2010 4:57 pm

by scorpion » Wed Sep 29, 2010 4:57 pm

Pretty encouraging news.

0 Replies

1833 Views

Last post by scorpion
Wed Sep 29, 2010 4:57 pm
Oral MS drug Cladribine rejected by European drug agency

Last post by LR1234 « Fri Sep 24, 2010 2:27 am
Replies: 1
by MSUK » Fri Sep 24, 2010 1:32 am

First post

European regulators rejected Merck KGaA’s multiple sclerosis pill cladribine, the second setback this week for the German drugmaker seeking to...

Last post

Isn't mad that some countries say ok to what could be very dangerous drugs whilst others feel the risk is too high??

Well lets see what happens with...

1 Replies

2201 Views

Last post by LR1234
Fri Sep 24, 2010 2:27 am
US priority review status for oral MS drug Cladribine

Last post by MSUK « Tue Jul 27, 2010 11:41 pm

by MSUK » Tue Jul 27, 2010 11:41 pm

German pharmaceutical and chemicals company Merck KGaA has announced that the U.S. Food and Drug Administration accepted a new drug application for...

0 Replies

1946 Views

Last post by MSUK
Tue Jul 27, 2010 11:41 pm
Multiple Sclerosis Market Forecast

Last post by erinc14 « Sun Jul 25, 2010 7:26 am

by erinc14 » Sun Jul 25, 2010 7:26 am

Multiple Sclerosis Market Forecast. With FDA advisory board support for Gilenia (fingolimod), Novartis will move ahead of Merck Serono's oral...

0 Replies

2246 Views

Last post by erinc14
Sun Jul 25, 2010 7:26 am
Russia first to approve oral MS drug...

Last post by Jawz78 « Thu Jul 15, 2010 6:23 pm
Replies: 1
by Jawz78 » Thu Jul 15, 2010 6:22 pm

First post

This is really cool... it sucks for me, because I do not live in Russia, but it is a step in the right direction...

--->
Tuesday July 13, 2010...

Last post

and I forgot the link... but did find an update

1 Replies

2050 Views

Last post by Jawz78
Thu Jul 15, 2010 6:23 pm
A new era of Multiple Sclerosis therapies begins

Last post by MSUK « Wed Jul 14, 2010 11:31 pm

by MSUK » Wed Jul 14, 2010 11:31 pm

New and improved multiple sclerosis (MS) drugs satisfying key unmet needs of oral administration and increased efficacy suggest a paradigm shift in...

0 Replies

1897 Views

Last post by MSUK
Wed Jul 14, 2010 11:31 pm
Cladribine tablets for Multiple Sclerosis approved in Russia

Last post by MSUK « Mon Jul 12, 2010 12:26 am

by MSUK » Mon Jul 12, 2010 12:26 am

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, announced today that the Russian Federal Service on Surveillance in Healthcare and Social...

0 Replies

1835 Views

Last post by MSUK
Mon Jul 12, 2010 12:26 am
Cladribine?

Last post by librajen « Mon Jun 28, 2010 5:03 pm

by librajen » Mon Jun 28, 2010 5:03 pm

Is anyone on this? How is it working for you? My neuro mentioned having me on it after the CCSVI treatment (on July 20 Yayyyyyyyyyy!!!!!!!!!!!!)

He...

0 Replies

1830 Views

Last post by librajen
Mon Jun 28, 2010 5:03 pm
Oral MS drug Cladribine 'Shuts Down MS Activity'

Last post by viper498 « Thu Jun 10, 2010 4:57 am
Replies: 2
by MSUK » Wed Jun 09, 2010 2:53 am

First post

Cladribine, an oral drug already marketed for hematologic cancers under the trade name Leustatin, was superior to placebo in reducing progression and...

Last post

Agreed. They could be feeding the media, or lying about the numbers. Who knows? I can't help being cynical myself.

2 Replies

2567 Views

Last post by viper498
Thu Jun 10, 2010 4:57 am
Merck KGaA refiles oral Multiple Sclerosis drug Cladribine

Last post by MSUK « Tue Jun 08, 2010 10:13 pm

by MSUK » Tue Jun 08, 2010 10:13 pm

German pharmaceutical and chemicals company Merck KGaA said Tuesday it resubmitted its application for U.S. regulatory approval of oral multiple...

0 Replies

1831 Views

Last post by MSUK
Tue Jun 08, 2010 10:13 pm
ONWARD Trial- Oral Cladribine with Avonex

Last post by patientx « Thu Mar 25, 2010 10:10 am
Replies: 1
by BooBear » Thu Mar 25, 2010 9:35 am

First post

I am a participant in the Oracle trial (oral cladribine, a chemo drug, twice a year with continued Avonex).

This is a double-blind study, so I...

Last post

I would like to hear continuing updates.

It sounds like the MS has been pretty aggressive. You neuro doesn't recommend a treatment any more...

1 Replies

2884 Views

Last post by patientx
Thu Mar 25, 2010 10:10 am
Cladribine

Last post by burntsienna « Wed Jan 27, 2010 12:08 pm
Replies: 3
by Lars » Fri May 22, 2009 8:22 am

First post

As I continue to hear of Cladribine's push towards approval, it occurred to me that I haven't really heard a lot of discussion here about it. Has...

Last post

They're already applying for a license here in the UK. Which means it could be available by 2011 in the UK. However, I'm really not sure I like the...

3 Replies

3042 Views

Last post by burntsienna
Wed Jan 27, 2010 12:08 pm
FDA rejects Multiple Sclerosis drug Cladribine application

Last post by Needled « Mon Nov 30, 2009 9:18 am
Replies: 1
by MSUK » Mon Nov 30, 2009 8:09 am

First post

FDA rejects Multiple Sclerosis drug Cladribine application as 'incomplete'

U.S. regulators rejected as incomplete Merck KGaA's application to sell...

Last post

Bummer. I hope it doesn't take them too long to sort it out.
I also hope Novartis does better with their app for Fingolimod. Novartis said they had...

1 Replies

2373 Views

Last post by Needled
Mon Nov 30, 2009 9:18 am
Cladribine pills

Last post by ewizabeth « Sun Oct 04, 2009 12:57 pm
Replies: 4
by Needled » Thu Aug 06, 2009 12:18 pm

First post

Merck submitted an application for Cladribine pills in Europe. They’re also submitting new drug applications for Cladribine tablets in other...

Last post

My doctor mentioned this medication to me on Friday when I was in for my infusion. I'm in a relapse and so I suppose he wanted me to know this one...

4 Replies

3426 Views

Last post by ewizabeth
Sun Oct 04, 2009 12:57 pm
Cladribine - Phase III results

Last post by Needled « Thu Apr 30, 2009 3:20 pm
Replies: 3
by Frank » Thu Apr 30, 2009 3:42 am

First post

Oral Multiple Sclerosis drug, Cladribine, appears effective, but cancer cases raise concerns

Merck KGaA reported late-stage data showing that its...

Last post

Hi Dave, Just to be clear, all of my comments were directed toward the pricing, not the drug itself. I'm with you -- I've been waiting on Fingolimod...

3 Replies

3256 Views

Last post by Needled
Thu Apr 30, 2009 3:20 pm
Cladribine results

Last post by dignan « Sat Jan 24, 2009 12:25 pm
Replies: 11
by bromley » Fri Jan 23, 2009 4:46 am

First post

Dignan,

You''ll have to get up earlier to beat me.

Ian

Last post

The cladribine plus rebif trial reminds me...that's another reason they could get approval with the results from only one trial: because there is a...

11 Replies

4015 Views

Last post by dignan
Sat Jan 24, 2009 12:25 pm
Who wants a marketing job with Serono?

Last post by patientx « Fri Jan 23, 2009 7:08 am
Replies: 1
by dignan » Thu Jan 22, 2009 9:56 pm

First post

Serono is hiring a team leader for the Cladribine Consumer Marketing Team.

This is fascinating for two reasons: 1. Serono sounds confident that...

Last post

Pretty interesting. Good post Dignan.

1 Replies

2205 Views

Last post by patientx
Fri Jan 23, 2009 7:08 am
Cladribine (Mylinax)

Last post by patientx « Wed Dec 03, 2008 5:36 pm

by patientx » Wed Dec 03, 2008 5:36 pm

In Dignan's recent post on phase III trial end dates, he mentioned Cladribine. I talked with the nurse coordinator at the MS center near me and asked...

0 Replies

2477 Views

Last post by patientx
Wed Dec 03, 2008 5:36 pm
Cladribine Phase-II results

Last post by gwa « Wed Apr 23, 2008 2:23 pm
Replies: 3
by Frank » Wed Apr 23, 2008 7:18 am

First post

The placebo controled phase-II trial treated 52 patients over 18 month.
Effects on relapses were significant, but no difference were seen regarding...

Last post

The people that have posted on these forums who claim to have gotten better, ie reversal of symptoms, can be counted on less than 10 fingers. None of...

3 Replies

3069 Views

Last post by gwa
Wed Apr 23, 2008 2:23 pm
Cladribine - one for Lyon

Last post by Lyon « Wed Jun 13, 2007 5:26 am
Replies: 1
by bromley » Wed Jun 13, 2007 5:10 am

First post

Lyon,

Now that you have ditched that dreadful shiny shirt and have signed up to the hair-transplant, I thought I'd reward you the research results...

Last post

Now that you have ditched that dreadful shiny shirt and have signed up to the hair-transplant, I thought I'd reward you the research results you like...

1 Replies

2346 Views

Last post by Lyon
Wed Jun 13, 2007 5:26 am
Cladribine + Rebif

Last post by scoobyjude « Wed Jan 24, 2007 7:47 pm
Replies: 2
by bromley » Wed Jan 24, 2007 5:29 am

First post

Merck Serono Has Initiated the ONWARD Study to Evaluate Oral Cladribine as Add-on Treatment for Multiple Sclerosis

ONWARD Phase II Trial Will...

Last post

Good point Sharon. Although I have to admit that if Cladribine proves to be about as effective as Rebif (however effective it actually is), there is...

2 Replies

2883 Views

Last post by scoobyjude
Wed Jan 24, 2007 7:47 pm
Oral cladribine Phase III

Last post by connieb « Tue Jan 16, 2007 7:36 pm
Replies: 2
by bromley » Tue Jan 16, 2007 2:21 am

First post

Merck Serono Completes Patient Enrollment in CLARITY Phase III Pivotal Clinical Trial of Oral Cladribine

Oral Cladribine on Track to Become First...

Last post

Is this the drug that had an effect on lesions but didn't do much for either disability progression or relapses? Or am I confusing it with something...

2 Replies

2796 Views

Last post by connieb
Tue Jan 16, 2007 7:36 pm
Oral Cladribine

Last post by amelia « Fri Sep 22, 2006 2:27 pm
Replies: 9
by bromley » Thu Sep 21, 2006 1:27 am

First post

Serono's Oral Cladribine for the Treatment of Multiple Sclerosis Awarded Fast Track Status by FDA

Serono announced today that oral cladribine has...

Last post

And don't forget the side effects:
weight gain
weight loss
diarrhea
constipation
headaches
drowiness
insomnia
sexual side effects
etc.................

9 Replies

3493 Views

Last post by amelia
Fri Sep 22, 2006 2:27 pm
Fast Track Status Granted for Multiple Sclerosis Treatment

Last post by gwa « Thu Sep 21, 2006 5:20 pm
Replies: 3
by Lyon » Thu Sep 21, 2006 2:31 pm

First post

oo

Last post

This drug is being discussed on the Drug Pipeline forum

I am underwhelmed with it unless there is a LOT more to know than what has been stated so...

3 Replies

2654 Views

Last post by gwa
Thu Sep 21, 2006 5:20 pm

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