(NAC) N Acetyl Cysteine please help if you know

[Ben21]

I'm wondering if anyone here knows anything about this because I hear it is also being used to treat MS

I have been taking (NAC) N Acetyl Cysteine for OCD treatment as an NDMA antagonist, and it seems to work pretty well. I am taking 600mg every six hours. Is is safe to up my daily dosage to 3600 mg? The very first time I took it I felt a kick after about 30 minutes. It doesn't appear to work the full six hours and there are sustained release tablets that are 600 mg but they are dispersed over time and are therefore less potent.

I also had to deal with some tremors and fasiculations and this seems to help out a lot with that.

I want to take one immediate release and one sustained release three times daily for a total of 3600 mg daily. Is this safe?
My doctor does not know enough about it to tell me what the negative side effects could be.
Some people have said that it will cause pulmonary hypertension. Does anyone have experience with this or know anyone who does?

Please don't tell me to go consult someone I have been dealing with this for the past five years of my life and I finally found something that gives me relief.

[bartman]

Ben21,
The place to go for an answer to this question is either CPn Help or the antibiotic section in this forum. Nac is part of the wheldon protocol, you might want to check it out because it works, it just takes a long time!
Good luck

[cheerleader]

Hi Ben---
working with a doctor is always advisable, especially for contraindications with other medicines/supplements you may be taking. You might go to an OCD message board, for info from people who understand your condition. We focus on MS here.
Excess glutamate is one connection between the use of NAC in MS and in OCD---

I'm not a doc, but I've researched NAC as a supplement to help endothelial dysfunction, or vasoconstriction, found in cardiovascular and cerebrovascular disease. It shouldn't cause hypertension, since NAC relaxes vessels, and enhances nitric oxide distribution--
http://www.ncbi.nlm.nih.gov/pubmed/21713097

It's a wonderful antioxidant, and decreases inflammation. It's also helpful dealing with abnormal glutamate levels in OCD-
http://www.ocfoundation.org/glutamate.aspx

That said, you are taking a high dosage. The highest dosage I've seen used in clinical trials in 2000 mg. (1000 mg. twice a day) Please be careful. More is not always better,
cheer

[Absentee]

this is interesting...does anyone have a suggestion for daily dosage of NAC?

[SarahLonglands]

2400mg divided in two doses as here: http://www.davidwheldon.co.uk/ms-treatment.pdf ...................Sarah