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Epilepsy drug 'could help multiple sclerosis patients'

Posted: Tue Jan 26, 2016 3:29 am
by MSUK
An anti-convulsant drug used to treat epilepsy may also prevent nerve damage in patients with multiple sclerosis (MS), research has shown...Read more - http://www.ms-uk.org/MSnews

Re: Epilepsy drug 'could help multiple sclerosis patients'

Posted: Thu Feb 11, 2016 1:51 pm
by frodo
MSUK wrote:An anti-convulsant drug used to treat epilepsy may also prevent nerve damage in patients with multiple sclerosis (MS), research has shown...Read more - http://www.ms-uk.org/MSnews
Great news!! Finally somebody focuses in the big problem, instead of loosing time with the absurd theory of the myelin, which is known to be unrelated to dissability.

Re: Epilepsy drug 'could help multiple sclerosis patient

Posted: Thu Feb 11, 2016 4:00 pm
by PointsNorth
I cannot find the article in the link provided.

Re: Epilepsy drug 'could help multiple sclerosis patients'

Posted: Thu Feb 11, 2016 5:04 pm
by CureOrBust
Historically I have found that MSUK's posts sometimes take a while before they are actually available on the corresponding website for view. But if you do a general web search, the article would of been posted by the general news publications also.
http://www.dailymail.co.uk/wires/pa/art ... ients.html
http://www.telegraph.co.uk/news/health/ ... rosis.html

I did find the following interesting "The drug works because it prevents the fatal build-up of sodium in nerve cells."

But, a side effect is "cerebellar ataxia". like I need more of that.

Re: Epilepsy drug 'could help multiple sclerosis patient

Posted: Thu Feb 11, 2016 5:15 pm
by NHE
PointsNorth wrote:I cannot find the article in the link provided.
It has already been bumped into the archive at http://www.ms-uk.org/jan2016 Scroll down a few articles and you should find it or search for the phrase "epilepsy drug."

Re: other MS-UK stories...

Posted: Thu Feb 11, 2016 8:13 pm
by 1eye
I noticed this story had been bumped and did not make it here, but:
New test claims to predict disability progression (26/01/16)
By noting the presence of certain markers in a commonly performed diagnostic test, researchers at the Mayo Clinic say they can predict whether multiple sclerosis patients will suffer a faster onset of disability and counsel them to help ease anxiety.

The research is to be presented at the American Academy of Neurology meeting in Honolulu, Hawaii.

“In this study, we found in patients who developed the progressive form of MS that had preceding relapses, the presence of greater production of immunoglobulin G predicted a faster onset of disability,” explains Orhun Kantarci, M.D., a Mayo Clinic neurologist and the study’s lead author.

The study looked at cerebrospinal fluid (CSF) test results from a sample of 281 progressive MS patients seen at Mayo Clinic from 2002 to 2007. In general, CSF test results help medical staff when the diagnosis is uncertain. For this study, researchers analysed CSF test results and noticed a relationship between a faster disability rate and abnormally high levels of two proteins — oligoclonal band and immunoglobulin-G molecule. If patients had the progressive form of MS with proceeding relapses, and their CSF results showed an elevated protein, researchers concluded they will have a faster rate of disability.

The study is a significant step forward in predicting disability outcomes, says researcher Junger Tang, M.D., a neurology fellow at Mayo Clinic. The next step is further research to confirm the results, he says.

Source: Health Got Mojo (26/01/16)
I think it is clear that the cause of MS and of MS disability resides in the CSF. That's why the mouse model with MS patient's CSF works. That's why the ELISA array is so completely specific in testing for MS. Now if they would just start using all those existing MRIs to track atrophy. What are they afraid of? That we might start learning too much about MS, and perhaps endanger the existing $15B drug industry?