Stanford successfully injects stem cells directly into brain
Stanford successfully injects stem cells directly into brain
http://www.telegraph.co.uk/science/2016 ... -cells-in/
- 1eye
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Re: Stanford successfully injects stem cells directly into b
Not a doctor.
Re: Stanford successfully injects stem cells directly into b
http://med.stanford.edu/news/all-news/2 ... ients.htmlAlthough more than three-quarters of them suffered from transient headaches afterward — probably due to the surgical procedure and the physical constraints employed to ensure its precision — there were no side effects attributable to the stem cells themselves, and no life-threatening adverse effects linked to the procedure used to administer them.
And it might work for MS.
Under standard procedures there are two more phases of tests to be done before the procedure can be marketed. https://en.wikipedia.org/wiki/Phases_of ... l_research
Those will likely take several years. In the meantime hundreds of thousands of patients with strokes, MS, ALZ, Parkinson's and Alzheimer’s will grow worse and edge closer to death ... or worse.
If its safe why not let patients have the procedure at their own discretion? The worst that could happen is that it won't work. Why all the extra phases? Could it be that they're making it too safe and depriving patients of the only treatment that might save them?
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Re: Stanford successfully injects stem cells directly into b
Wouldn't want any complications from lethal injections, after all, would we? For one thing, those lawyers might sue us. That could get, well, complicated.
Something adverse might happen, that could lead to death... or worse. Or more complicated.
Not a doctor.
Re: Stanford successfully injects stem cells directly into b
He told me in an appt last week that studies using drugs are easily approved due to the drug companies paying for them - but just try and do a study that doesn't involve drugs.....
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Re: Stanford successfully injects stem cells directly into b
Crowd-funding might also work.
You can be damn sure when time comes to protect IP some drug company will call it a drug no matter if it is or not. If the stem cells are human they'll claim something is exclusively theirs, probably patenting some process or other. Then the FDA will really get interested. Hope the trial happens without them.
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Re: Stanford successfully injects stem cells directly into b
He mentioned though that their biggest push is to get involved with medical pot!! He said that where they see the money is at.
Re: Stanford successfully injects stem cells directly into b
Sure. We're not the only ones watching Sanjay Gupta's Weed documentary. When they watch it, they probably start salivating like hungry wolves.jay123 wrote:He mentioned though that their biggest push is to get involved with medical pot!! He said that where they see the money is at.
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Re: Stanford successfully injects stem cells directly into b
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Re: Stanford successfully injects stem cells directly into b
Just a guess, but I would assume they are injecting the stem cells into the spinal fluid, which surrounds the brain and is shared with the brain.Vivianne766 wrote:Regarding Stanford study for injecting stem cells in the brain. In case of MS , what if the damage is mostly in the spine not the brain?
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Re: Stanford successfully injects stem cells directly into b
According to the article in The Telegraph:CureOrBust wrote:Just a guess, but I would assume they are injecting the stem cells into the spinal fluid, which surrounds the brain and is shared with the brain.Vivianne766 wrote:Regarding Stanford study for injecting stem cells in the brain. In case of MS , what if the damage is mostly in the spine not the brain?
So it appears it was only tried on stroke patients so far, and only injected around the edges of that specific area of damage. Although it's a great discovery with potential for other kinds of brain injuries, I also wonder how they would adapt this to MS patients like me, who have too many lesions to count, in every part of their brain (no spinal lesions).All the patients involved in the trial had suffered ischemic strokes where a clot prevents blood getting to the brain, which leads to brain cell death. The procedure involved drilling a small hole in the skull above the damaged area so that SB623 stem cells could be injected at several spots around the edge of the injury.
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Re: Stanford successfully injects stem cells directly into b
euphoniaa wrote:According to the article in The Telegraph:CureOrBust wrote:Just a guess, but I would assume they are injecting the stem cells into the spinal fluid, which surrounds the brain and is shared with the brain.Vivianne766 wrote:Regarding Stanford study for injecting stem cells in the brain. In case of MS , what if the damage is mostly in the spine not the brain?All the patients involved in the trial had suffered ischemic strokes where a clot prevents blood getting to the brain, which leads to brain cell death. The procedure involved drilling a small hole in the skull above the damaged area so that SB623 stem cells could be injected at several spots around the edge of the injury.


Hopefully to redeem my indiscretioneuphoniaa wrote:So it appears it was only tried on stroke patients so far, and only injected around the edges of that specific area of damage. Although it's a great discovery with potential for other kinds of brain injuries, I also wonder how they would adapt this to MS patients like me, who have too many lesions to count, in every part of their brain (no spinal lesions).

http://www.businesswire.com/news/home/2 ... t-Patients This Japanese group appear to plan to bring it to market ASAP under some quick approval scheme in Japan.
They all seem to inject it directly into the brain near the site if damage, but its hard to believe there is no "leakage" of benefits beyond a small area surrounding the injection site. But we all know where assumptions got me previously...

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Re: Stanford successfully injects stem cells directly into b
https://www.washingtonpost.com/news/to- ... ient-walk/
The "miraculous" results seem pretty marginal to me. The journalists really took liberties in their descriptions. This could easily just be the placebo effect, physical therapy, optimism. My guess is that in a randomized double blind trial, it will have no benefit versus the sham procedure. I would be interested to see the results though.
Sorry to be so pessimistic, but we can't drill holes into everyone's skull unless a procedure is actually proven to work first. If anecdotes are enough to convince us, we should go back to blood letting.
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Re: Stanford successfully injects stem cells directly into b
Not a doctor.
Re: Stanford successfully injects stem cells directly into b
With the evil powers-that-be at work, this study might be washed away into oblivion.
How incredible it would be to participate in a similar study run on MS'ers

And I wonder WHY so few people have watched that incredible video:
https://www.youtube.com/watch?v=VGuBMroX7c8
ipek
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