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Cerebral microbleeds in MS patients....

Posted: Fri Jun 17, 2016 2:00 am
by MSUK
Cerebral microbleeds in MS patients associated with increased risk of disability

Leaky blood vessels in the brain called cerebral microbleeds are associated with increased physical and cognitive disability in patients with multiple sclerosis (MS), according to a new study by researchers in the Jacobs School of Medicine and Biomedical Sciences...Read more - http://www.ms-uk.org/MSnews

Re: Cerebral microbleeds in MS patients....

Posted: Fri Jun 17, 2016 5:19 am
by cheerleader
7T machines are allowing researchers to see beyond white matter lesions.
Plasmic particles leak thru "fragile" capillaries (a term used by Dr. Roy Swank in the 1950s)
Blood in brain tissue causes oxidative stress, demyelination, iron deposition and inflammation.
The vascular evidence continues.
Significant research is now being done on ways to combat cerebral microbleeds, Zivadinov said, adding that currently, prevention of cardiovascular risk factors was seen as the best way to prevent their formation since there are no currently available target therapies.
This is exactly why taking care of heart health is so vitally important. There are NO DRUGS to prevent cerebral microbleeds. It is why I created the Endothelial Health Program to combat all of the environmental factors which contribute to the weakening of the endothelial cells. A strong endothelium keeps blood inside vessels. It's not a pill, it's a lifestyle.

More on the published research here:
http://ccsviinms.blogspot.com/2016/06/c ... nd-ms.html

cheer

Re: Cerebral microbleeds in MS patients....

Posted: Fri Jun 17, 2016 6:25 am
by CureOrBust
The current study does not appear to be available, but the following link has some (ie a little) info not in the above: http://pubs.rsna.org/doi/pdf/10.1148/radiol.2016160060

Although there may not be any anti-CMB drugs, it appears that many (commonly used by CCSVI treated patients) are not good.
http://cvd.sagepub.com/content/1/8/22.full
In ischaemic stroke from causes other than cardiac embolism (in which anticoagulation is generally preferred), antiplatelet medications are a key component of secondary prevention of future occlusive vascular events. Aspirin is the most widely studied agent, and carries only a small absolute risk of symptomatic ICH of less than 0.5%,39 though this risk seems to be higher in Asian than in non-Asian cohorts. There has been concern that antiplatelet drugs could not only cause CMBs but also increase the risk of symptomatic ICH.

Re: Cerebral microbleeds in MS patients....

Posted: Fri Jun 17, 2016 7:06 am
by cheerleader
As dicussed at ISNVD this year, pulsatile flow creates a risk for CMBs.
http://stroke.ahajournals.org/content/4 ... 1.abstract
http://isnvd.org/sites/default/files/Ac ... 20Oral.pdf

Treating venous outflow abnormalities (with a temporary use of anti-coagulation therapy) allows for better laminar flow, a healthier cerebral endothelium and potentially stronger blood brain barrier. http://bmcneurosci.biomedcentral.com/ar ... 2202-12-40
cheer

Re: Cerebral microbleeds in MS patients....

Posted: Sat Jun 18, 2016 10:19 am
by Leonard
it's the zoster virus cheer, it's the zoster virus that causes the microbleeds.

look for articles from Maria Nagel.

The Varicella Zoster virus or VZV is an inflammatory virus.