I have just read in MS-UK that Simvastatin trial is gonna start ... 10 years late.
As it happened already with Rituxan, Simvastatin is a drug with a expired patent, and though patent expiration is supposed to be something for the public interest, the effect is that nobody has performed a real clinical trial in a lot of years.
Until now. Finally the MS Society, the NIHR and the National MS Society have found the funds. Maybe somebody around here with SPMS could be interested.
http://www.ms-uk.org/ms-patients-trial- ... ent-090517
Simvastatin trial starting
Re: Simvastatin trial starting
http://www.thelancet.com/journals/lance ... S0140-6736(13%2962242-4/abstract
lipid peroxydation is the major issue in the progressive disease.
lowering LDL cholesterol will slow progression.
lipid peroxydation is the major issue in the progressive disease.
lowering LDL cholesterol will slow progression.
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Re: Simvastatin trial starting
I have been doing my own trial for years. Simvastatin is almost the official drug of South Louisiana due to the diet around here...rich in fat.
So I'm just a testimonial. I have been taking (40mg) Simvastatin since 1996. I was dx'd with MS 2/2016 just a week before my 59 th birthday.
So, does Simvastatin slow the disease?
.......No because I got the disease.
.......Yes because I was dx'd at such a late age.
Looks like a more comprehensive test is needed....
So I'm just a testimonial. I have been taking (40mg) Simvastatin since 1996. I was dx'd with MS 2/2016 just a week before my 59 th birthday.
So, does Simvastatin slow the disease?
.......No because I got the disease.
.......Yes because I was dx'd at such a late age.
Looks like a more comprehensive test is needed....
- Quest56
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Re: FDA Warnings About Simvastatin Use
FDA warnings about high-dose simvastatin use (80mg) from 2011:
https://www.fda.gov/Drugs/DrugSafety/ucm256581.htm
https://www.fda.gov/Drugs/DrugSafety/ucm256581.htm
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