This Is MS Multiple Sclerosis Knowledge & Support Community
Welcome to This is MS, the leading forum for Multiple Sclerosis research and support. Join our friendly community of patients, caregivers, and researchers celebrating over 20 years of delivering hope through knowledge. https://www.thisisms.com/forum/
... This is a dentist treating himself with IV ozone. I've used it in my veterinary practice for three years. I've treated myself exactly as he does in the video. The theory is that ozone 'energizes' the blood. The theory states that most disease is the result of poor oxygen levels. Ozone causes the 2, 3 DPG enzyme to release oxygen from hemoglobin more readily. Last night I had severe pain from an embolus in my arm. I may try the IV ozone.
Re: ozone
Posted: Sat Dec 30, 2017 1:44 pm
by ElliotB
There seems to be some controversy with ozone therapy. I do oxygen therapy which seems to be a safer option. Both methods are thought to be beneficial.
Re: ozone
Posted: Sat Dec 30, 2017 7:55 pm
by NHE
Ozone is an oxidant. In some countries ozone is used to treat drinking water to help kill any microorganisms.
Re: ozone
Posted: Sat Dec 30, 2017 10:11 pm
by koneall
Medical use requires microgram levels of ozone. Milligram or gram amounts will sterilize water but are toxic to tissue. The DVT pain went away during the treatment earlier.
kaypeeoh
Re: ozone
Posted: Sun Dec 31, 2017 1:32 am
by Kittie
I have used Oxygen Elements Max for the last 15 years and energy levels good since using it. It also cleanses water.
Kittie.
Re: ozone
Posted: Sun Dec 31, 2017 6:04 pm
by koneall
No pain during the night. But it came back midday. I spent an hour on the track and the pain was never bad enough to consider taking drugs.
Because ozone can be administered by lay people, it might be worth looking into. I have an ozone generator which can produce ozone at medical grade concentrations. It can be given IV or it can be infused into the rectum. IVs are out of the average person's knowledge but an ozone enema can be done by anyone. It's been shown that ozone enters the bloodstream through the colon and hepatic portal system nearly as quickly as an IV. Medical grade generators range in price from $500 to $2500. Insurance generally does not cover ozone treatments.
Re: ozone
Posted: Sat Dec 17, 2022 8:01 am
by Petr75
2022 Dec 2
Faculty of Environmental Sciences and Biochemistry, University of Castilla-La Mancha, Toledo, Spain Ozone modified hypothalamic signaling enhancing thermogenesis in the TDP-43A315T transgenic model of Amyotrophic Lateral Sclerosis https://pubmed.ncbi.nlm.nih.gov/36460700/
Abstract
Amyotrophic lateral sclerosis (ALS), a devastating progressive neurodegenerative disease, has no effective treatment. Recent evidence supports a strong metabolic component in ALS pathogenesis. Indeed, metabolic abnormalities in ALS correlate to disease susceptibility and progression, raising additional therapeutic targets against ALS. Ozone (O3), a natural bioactive molecule, has been shown to elicit beneficial effects to reduce metabolic disturbances and improved motor behavior in TDP-43A315T mice. However, it is fundamental to determine the mechanism through which O3 acts in ALS. To characterize the association between O3 exposure and disease-associated weight loss in ALS, we assessed the mRNA and protein expression profile of molecular pathways with a main role in the regulation of the metabolic homeostasis on the hypothalamus and the brown adipose tissue (BAT) at the disease end-stage, in TDP-43A315T mice compared to age-matched WT littermates. In addition, the impact of O3 exposure on the faecal bacterial community diversity, by Illumina sequencing, and on the neuromuscular junctions (NMJs), by confocal imaging, were analysed. Our findings suggest the effectiveness of O3 exposure to induce metabolic effects in the hypothalamus and BAT of TDP-43A315T mice and could be a new complementary non-pharmacological approach for ALS therapy.
Re: ozone
Posted: Tue Feb 21, 2023 11:08 am
by Petr75
2022 Sep 21
Division of Oral Implantology, Faculdade São Leopoldo Mandic, Campinas, SP, Brazil Effect of ozone therapy on the modulation of inflammation and on new bone formation in critical defects of rat calvaria filled with autogenous graft https://pubmed.ncbi.nlm.nih.gov/36150689/
Abstract
Objective: The aim of this study was to evaluate the effect of ozone therapy on new bone formation and inflammation modulation in defects of rat calvaria filled with autogenous bone.
Material and methods: Critical size defects were created in the calvaria of 24 male Wistar rats. The animals were randomly divided into four groups according to the treatment: G1: clot; G2: clot and covered with xenogenic membrane; G3: particulate autogenous bone graft; G4: autogenous bone graft and application of 3 mL O2/O3 gas mixture (10 µg/ml). The defects were filled immediately after surgery with a bilateral retroauricular application, in the region immediately above the incision. After 21 days, the animals were euthanized, and the samples were processed for morphometric evaluations designed to measure both the intensity of the inflammatory infiltrate, and the presence of new bone formation in the defect.
Results: The results showed a lower inflammation score and higher mean of newly formed bone in the region of the defect for the group associated with ozone therapy (G4). The bone formed in the region of the defect could be observed as being more lamellar and mineralized in the case of associated ozone therapy.
Re: ozone
Posted: Sun Mar 31, 2024 3:46 am
by Petr75
2024 Mar 26
Chemistry Center of Vila Real, University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal Impact of ozone therapy on mouse liver mitochondrial function and antioxidant system https://pubmed.ncbi.nlm.nih.gov/38548043/
Abstract
Ozone therapy's efficacy might stem from the regulated and mild oxidative stress resulting from ozone's interactions with various biological elements. The present work aimed to characterize the hepatic mitochondrial response to ozone treatment and its relationship with the antioxidant system response. Two groups of mice were used: one control group and another injected intraperitoneally with an O3/O2 mixture (80 ml/kg) for 5 days. Mitochondrial respiration supported by different substrates was significantly inhibited, as well as complexes I and II/III, but not complex IV. The analysis of the electron transport chain complex activity showed significant inhibitions in complexes I and II/III but not in complex IV. These inhibitions can prevent mitochondrial reactive oxygen species (ROS) production. Additionally, there was a decline in glutathione content, unaccompanied by a rise in its oxidized form. The ozone-treated groups showed a significant increase in the activity of superoxide dismutase and glutathione peroxidase, while catalase and glutathione reductase experienced no significant alterations. Adenine nucleotides increased in the ozone group, but only the increase in adenosine diphosphate is significant, so the cell's energy charge is unaffected. This study shows that mitochondria may play a crucial role in ozone treatment. However, it also highlights the need for further studies to understand the molecular mechanism.