Cross-talks between the kidneys and the CNS

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Cross-talks between the kidneys and the CNS

Post by Petr75 » Mon Oct 01, 2018 8:40 am

2018 Summer
Department of Clinical Biochemistry, Faculty of Medicine, Tarbiat Modarres University, Tehran, Iran
Cross-talks between the kidneys and the central nervous system in multiple sclerosis

Multiple sclerosis (MS) is an inflammatory demyelinating disease, which is considered as a common autoimmune disorder in young adults. A growing number of evidences indicated that the impairment in non-neural tissues plays a significant role in pathology of MS disease. There are bidirectional relationship, metabolic activities and functional similarity between central nervous system (CNS) and kidneys which suggest that kidney tissue may exert remarkable effects on some aspects of MS disorder and CNS impairment in these patients compels the kidney to respond to central inflammation. Recently, it has been well documented that hormonal secretion possesses the important role on CNS abnormalities. In this regard, due to the functional similarity and significant hormonal and non-hormonal relationship between CNS and kidneys, we hypothesized that kidneys exert significant effect on initiation, progression or amelioration of MS disease which might be regarded as potential therapeutic approach in the treatment of MS patients in the future.

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Re: Cross-talks between the kidneys and the CNS

Post by jimmylegs » Mon Oct 01, 2018 8:55 am

not sure of the connections or relevance but i do know that my inflammatory skin issues respond very favourably to topical use of a synthetic derivative of a kidney output product, namely 1,25 dihydroxyvitamin d3.

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