Prevalence of asthma in multiple sclerosis

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Petr75
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Prevalence of asthma in multiple sclerosis

Post by Petr75 » Sat Jan 19, 2019 9:34 pm

2018 Dec 12
Neuroimmunological Disorders Gene-Environment Epidemiology Laboratory, Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland
Prevalence of asthma in multiple sclerosis: A United States population-based study
https://www.ncbi.nlm.nih.gov/pubmed/30557818

Abstract
BACKGROUND:
Multiple sclerosis (MS) and asthma are complex multifactorial diseases which adversely impact daily functioning. However, the prevalence of asthma in those with MS is not clear. The objective of this study is to characterize the prevalence of asthma in those with MS, with considerations for age, gender, and race.
METHODS:
We conducted a U.S. population-based, cross-sectional study of electronic health record information for 56.6 million Americans available in the IBM® Explorys EPM: Explore database. We evaluated the prevalence of asthma in MS (N = 141,880) and non-MS (N = 56,416,790) cohorts, stratifying by age, gender, and race (All, White Americans, and African Americans).
RESULTS:
The prevalence of asthma was significantly greater among those with MS than the general population across age, gender, and racial subpopulations. Adjusting for age and gender, asthma was three times more common in MS. In the MS cohort, the prevalence of asthma had a U-shaped distribution with respect to age, with the greatest asthma prevalence among the young and the elderly (> 20% prevalence among those <30 or ≥80 years; prevalence range: 15 to 30%); this significantly differed from the fairly uniform distribution observed in the non-MS cohort (prevalence range: 4 to 9%). These patterns were relatively consistent when stratifying by gender and race.
CONCLUSION:
Asthma is significantly more common in those with MS than in the general population - particularly in the young and elderly - irrespective of gender and race. The results add to the growing MS comorbidity literature, and emphasizes the need for comorbidity management as a part of comprehensive MS patient care.

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2019 Jan 18
Department of Geomatics Engineering, Marand Technical College, Tabriz University, Tabriz, Iran
A ubiquitous asthma monitoring framework based on ambient air pollutants and individuals' contexts.
https://www.ncbi.nlm.nih.gov/pubmed/30656587

Abstract

Air pollutants and allergens are the main stimuli that have considerable effects on asthmatic patients' health. Seamless monitoring of patients' conditions and the surrounding environment, limiting their exposure to allergens and irritants, and reducing the exacerbation of symptoms can aid patients to deal with asthma better. In this context, ubiquitous healthcare monitoring systems can provide any service to any user everywhere and every time through any device and network. In this regard, this research established a GIS-based outdoor asthma monitoring framework in light of ubiquitous systems. The proposed multifaceted model was designed in three layers: (1) pre-processing, for cleaning and interpolating data, (2) reasoning, for deducing knowledge and extract contextual information from data, and (3) prediction, for estimating the asthmatic conditions of patients ubiquitously. The effectiveness of the proposed model is assessed by applying it on a real dataset that comprised of internal context information including patients' personal information (age, gender, height, medical history), patients' locations, and their peak expiratory flow (PEF) values, as well as external context information including air pollutant data (O3, SO2, NO2, CO, PM10), meteorological data (temperature, pressure, humidity), and geographic information related to the city of Tehran, Iran. With more than 92% and 93% accuracies in reasoning and estimation mechanism, respectively, the proposed method showed remarkably effective in asthma monitoring and management.

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Leonard
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Re: Prevalence of asthma in multiple sclerosis

Post by Leonard » Mon Jan 21, 2019 12:59 am

Hi Petr,

See viewtopic.php?f=1&t=15188&p=256485#p256485 for an explanation of the comorbidity.

best, Leo

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Petr75
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Joined: Sat Oct 19, 2013 10:17 am
Location: Czech Republic

Re: Prevalence of asthma in multiple sclerosis

Post by Petr75 » Mon Jan 21, 2019 1:49 pm

Hi Leo
time 09:05

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