2007 Review: Reversible Cerebral Vasoconstriction Syndromes
Posted: Tue May 07, 2019 7:51 am
not specific to ms, but interesting...
Narrative Review: Reversible Cerebral Vasoconstriction Syndromes (2007)
https://www.ncbi.nlm.nih.gov/pubmed/17200220
"TREATMENT
Treatment for RCVS is guided by observational data because, to our knowledge, no clinical trials of any treatment for this disorder have been conducted. A therapeutic view of RCVS must be balanced by 2 opposing groups of observations. On the one hand, successful outcomes, including alleviation of symptoms and rapid reversibility of vascular abnormalities, have been reported with various methods of treatment, including calcium-channel blockers (38, 91); brief courses of glucocorticoids (36); magnesium sulfate (16); and most important, simple observation (1, 3, 36, 92). On the other hand, the clinical course may also be pernicious, and it is not uncommon for symptoms to clear initially only to return repeatedly within days, culminating in stroke (36, 38, 39). Stroke as an outcome has been reported in as many as 54% of patients in 1 review (37).
However, there are no clear clinical or imaging features that reliably predict outcome."
i wonder if that return of symptoms typically occurs during or after active treatment... no time to dig in on details via fft right now.
when checking to see if the above had already been posted, i realized something similar was already here:
viewtopic.php?p=255967#p255967
something to dig in on another time, perhaps. we'll see
Narrative Review: Reversible Cerebral Vasoconstriction Syndromes (2007)
https://www.ncbi.nlm.nih.gov/pubmed/17200220
"TREATMENT
Treatment for RCVS is guided by observational data because, to our knowledge, no clinical trials of any treatment for this disorder have been conducted. A therapeutic view of RCVS must be balanced by 2 opposing groups of observations. On the one hand, successful outcomes, including alleviation of symptoms and rapid reversibility of vascular abnormalities, have been reported with various methods of treatment, including calcium-channel blockers (38, 91); brief courses of glucocorticoids (36); magnesium sulfate (16); and most important, simple observation (1, 3, 36, 92). On the other hand, the clinical course may also be pernicious, and it is not uncommon for symptoms to clear initially only to return repeatedly within days, culminating in stroke (36, 38, 39). Stroke as an outcome has been reported in as many as 54% of patients in 1 review (37).
However, there are no clear clinical or imaging features that reliably predict outcome."
i wonder if that return of symptoms typically occurs during or after active treatment... no time to dig in on details via fft right now.
when checking to see if the above had already been posted, i realized something similar was already here:
viewtopic.php?p=255967#p255967
something to dig in on another time, perhaps. we'll see