Oral health

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Petr75
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Posts: 786
Joined: Sat Oct 19, 2013 10:17 am
Location: Czech Republic

Oral health

Post by Petr75 » Fri Dec 13, 2019 10:33 am

2019 Dec 9
School of Dentistry, The University of Queensland, Brisbane, Qld, Australia
A systematic review of oral health in people with multiple sclerosis.
https://www.ncbi.nlm.nih.gov/pubmed/31815299

Abstract
OBJECTIVES:
Despite more than 25 years of research focused on this topic, it remains unclear whether people with multiple sclerosis are more likely to present with oral health problems. The aim of this study was to provide the first systematic review of this literature.
METHODS:
A literature search for studies focused on oral health and multiple sclerosis was conducted using PRISMA guidelines. Electronic databases (PubMed, Scopus, Web of Science, MEDLINE and CINAHL) were searched up until February 2019. Two independent coders extracted data, and study quality graded using the Newcastle-Ottawa Scale (NOS).
RESULTS:
From 1281 articles identified, 17 met all the eligibility criteria. Of the seventeen studies, more than half included a nonclinical control group, and the majority were observational studies. The included studies were of poor to moderate quality. Taken together, the results provided only very limited evidence that people with multiple sclerosis are more likely to present with dental caries and gingival disease. There was suggestive evidence that people with multiple sclerosis may be at higher risk of periodontal disease and present with poorer oral hygiene, and moderate evidence for an association between multiple sclerosis and temporomandibular disorders.
CONCLUSIONS:
This systematic review provides evidence of an association between multiple sclerosis and at least some oral health problems. When temporomandibular disorders and periodontal status specifically have been assessed, most studies provide evidence of an association with multiple sclerosis. However, this review also clearly highlights the need for further, high-quality studies in this area.

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Petr75
Family Elder
Posts: 786
Joined: Sat Oct 19, 2013 10:17 am
Location: Czech Republic

Re: Oral health

Post by Petr75 » Thu May 07, 2020 8:19 pm

2020 Jan-Mar
Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Salivary profile and dental status of patients with multiple sclerosis
https://www.ncbi.nlm.nih.gov/pubmed/32307931

Abstract
BACKGROUND:
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system. The MS patients may display biochemical changes in their cerebrospinal fluid, peripheral blood and saliva. Since the salivary profile plays a critical role in maintaining oral health and function, the analysis of saliva in the MS patients would be beneficial to prevent oral diseases, such as dental caries.
OBJECTIVES:
The aim of this study was to evaluate the dental status and salivary profile of the MS patients.
MATERIAL AND METHODS:
The study involved 25 MS patients and 25 healthy controls who were examined with regard to the calcium and phosphorus level, pH and flow rate of saliva as well as the decayed, missing and filled teeth (DMFT) index for permanent first molars. Student's t-test, the χ2 test and the Mann-Whitney test were utilized to compare the study groups.
RESULTS:
Significantly lower salivary flow rates were observed in the MS patients as compared to the controls. The salivary calcium and phosphorus levels were significantly higher in the case group during the first 6 years of the disease and 6-11 years after the onset of the disease, respectively, in comparison with the controls; however, there was no significant difference between the groups in terms of pH. The DMFT index for permanent first molars was higher in the MS patients than in the healthy controls, but not significantly. The number of carious and missing permanent first molars was significantly higher in the MS patients.
CONCLUSIONS:
Multiple sclerosis appears to significantly change the salivary profile and dental status of the patients.

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