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High-Altitude Climbing

Posted: Mon Dec 16, 2019 11:55 am
by Petr75
2019 Dec 11
Department of Pediatrics, Medical Group, Yokota AB, APO, Japan
Multiple Sclerosis Exacerbation Associated With High-Altitude Climbing Exposure.
https://www.ncbi.nlm.nih.gov/pubmed/31825081
source https://academic.oup.com/milmed/advance ... chresult=1

Abstract
The spectrum of the neurological effects of high-altitude exposure can range from high-altitude headache and acute mountain sickness, to the more severe end of the spectrum with high-altitude cerebral edema. In general, patients with known unstable preexisting neurological conditions and those patients with residual neurological deficits from a preexisting neurological condition are discouraged from climbing to high altitudes because of the risk of exacerbation or worsening of symptoms. Although multiple sclerosis exacerbations can be triggered by environmental factors, high-altitude exposure has not been reported as a potential trigger. We are reporting the case of a multiple sclerosis exacerbation presenting in an active duty U.S. Air Force serviceman upon ascending and descending Mt. Fuji within the same day.


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why?

Re: High-Altitude Climbing

Posted: Tue Dec 17, 2019 2:34 am
by NHE
Petr75 wrote: Mon Dec 16, 2019 11:55 am------------------------------------------------------
why?

A hypothesis: Hypoxic stress on the mitochondria? Triggers neuronal apoptosis and activates the immune system secondarily to "clean things up."

Re: High-Altitude Climbing

Posted: Tue Dec 17, 2019 11:30 am
by Petr75
Yes, it is possible.
But I find it strange that there is no more MS in freediving. It's hard to say, it's more complicated. I know.