Coronavirus (COVID-19) Research

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NHE
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Re: Coronavirus (COVID-19) News

Post by NHE » Mon Jun 15, 2020 1:07 pm

FDA Withdraws Emergency Use Authorization For Hydroxychloroquine
June 15, 2020 2:30 PM ET

https://www.npr.org/sections/coronaviru ... hloroquine

The U.S. Food and Drug Administration today withdrew a special status known as emergency use authorization for the drugs chloroquine and hydroxychloroquine.

Emergency use authorization is designed to facilitate the availability of drugs needed during public health emergencies. It allows unapproved medical products or unapproved uses of approved medical products to be used in such emergencies.

President Trump was an early and vocal champion of the drugs, and even declared in May that he was taking the drugs to prevent COVID-19.

Hydroxychloroquine and chloroquine were initially designed as anti-malarial drugs and later shown to be useful in treating certain autoimmune disorders. Early on in the pandemic, some researchers thought the drugs might be useful in treating COVID-19. Laboratory tests showed hydroxychloroquine interfered with the ability of the coronavirus that causes COVID-19 to enter cells. There were also hints from the use of the drugs in patients that they might be helpful. The FDA granted the emergency use authorization in March.

But those early positive results came from small studies that did not stand up well to scientific scrutiny. Larger, more carefully designed studies failed to show a benefit.

"It is no longer reasonable to believe that oral formulations of [hydroxychloroquine] and [chloroquine] may be effective in treating COVID-19, nor is it reasonable to believe that the known and potential benefits of these products outweigh their known and potential risks," said FDA chief scientist Denise M. Hinton put it in the letter explaining the agency's decision.

The FDA decision does not affect the use of the drugs in approved clinical trials.

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Re: Coronavirus (COVID-19) News

Post by vesta » Fri Jun 19, 2020 7:45 am

NHE wrote:
Mon Jun 15, 2020 1:07 pm
FDA Withdraws Emergency Use Authorization For Hydroxychloroquine
June 15, 2020 2:30 PM ET

https://www.npr.org/sections/coronaviru ... hloroquine

The U.S. Food and Drug Administration today withdrew a special status known as emergency use authorization for the drugs chloroquine and hydroxychloroquine.

Emergency use authorization is designed to facilitate the availability of drugs needed during public health emergencies. It allows unapproved medical products or unapproved uses of approved medical products to be used in such emergencies.

President Trump was an early and vocal champion of the drugs, and even declared in May that he was taking the drugs to prevent COVID-19.

Hydroxychloroquine and chloroquine were initially designed as anti-malarial drugs and later shown to be useful in treating certain autoimmune disorders. Early on in the pandemic, some researchers thought the drugs might be useful in treating COVID-19. Laboratory tests showed hydroxychloroquine interfered with the ability of the coronavirus that causes COVID-19 to enter cells. There were also hints from the use of the drugs in patients that they might be helpful. The FDA granted the emergency use authorization in March.

But those early positive results came from small studies that did not stand up well to scientific scrutiny. Larger, more carefully designed studies failed to show a benefit.

"It is no longer reasonable to believe that oral formulations of [hydroxychloroquine] and [chloroquine] may be effective in treating COVID-19, nor is it reasonable to believe that the known and potential benefits of these products outweigh their known and potential risks," said FDA chief scientist Denise M. Hinton put it in the letter explaining the agency's decision.

The FDA decision does not affect the use of the drugs in approved clinical trials.
CHRONOLOGY
October 2019 Johns Hopkins Event 201. A preview ?
« The Johns Hopkins Center for Health Security in partnership with the World Economic Forum and the Bill and Melinda Gates Foundation hosted Event 201, a high-level pandemic exercise on October 18, 2019, in New York, NY. The exercise illustrated areas where public/private partnerships will be necessary during the response to a severe pandemic in order to diminish large-scale economic and societal consequences. »

December 2019 China confirms Coronavirus outbreak in Wuhan.
January 2020 French Minister of Health Agnès Buzyn requires medical prescription for Hydroxychloroquine (HCQ) after being available over-the-counter since 1955 (discovered 1934).
January 2020 Dr Didier Raoult declares confidence that the COVID 19 can be easily treated with HCQ which is very inexpensive.
March 2020 French govt forbids MDs to prescribe HCQ for COVID 19.
March 23 2020 Dr Zelenko of New York sends open letter to Pres Trump describing his successful treatment for Covid 19 using HCQ, Azithromycin and Zinc Sulfate.
President Trump takes Dr Zelenko’s work seriously which becomes a political rather than a scientific issue.
Prof Luc Montagnier declares he beleives COVID 19 was created in a lab, components of an AIDs virus having been inserted into a Corona virus.
Dr. Fauci denies this asserting that Covid 19 evolved naturally. Wikipedia : « Anthony Stephen Fauci is an American physician and immunologist who has served as the director of the National Institute of Allergy and Infectious Diseases (NIAID) since 1984. Since January 2020, he has been one of the lead members of the Trump Administration's White House Coronavirus Task Force addressing the COVID-19 pandemic in the United States
May 5, 2020 Dr Raoult posts his HCQ study on line.
22 May Dr Zelenko leaves his medical group under harrassment after 20 years.
22 May 2020 The Lancet study of hydroxychloroquine (HCQ) administered to nearly 100,000 hospitalized patients is published. It presumably proves that HCQ is both ineffective in treating Covid 19 and dangerous.
25 May WHO ceases all studies of HCQ.
27 May France forbids the prescribing of HCQ for COVID 19, abandons research
Italian, Belgian, Swiss govts follow suit.
27 May Dr. Didier Raoult posts study of 3,737 patients treated with HCQ for Covid 19.
28 May, 120 scientists, doctors, researchers (only 2 are French) send open letter to The Lancet critical of their May 22 study on HCQ. (Notice rapid response. My feeling is that scientists are tired of being obliged to lie for Big Pharma’s profit motive.)
2 June The Lancet issues « mise en guard »
3 June WHO resumes research on HCQ.
4 June Three of Four authors disavow The Lancet article
The French government still forbids prescribing HCQ for Covid 19.
Norwegian scientist considers Covid 19 to be lab made.

WHAT IS GOING ON ?
The declaration of Bill Gates that things can’t go « back to normal » until we have a vaccine to prevent Covid 19 is repeated by the Main Stream Meda (MSM), Dr. A Fauci and medical authorities everywhere. Why did WHO and various governments act so precipitously after the publication of the Lancet article ? Why has France blocked Dr Raoult’s successful HCQ treatment ? Why haven’t I seen a serious critique of his research ?

BILL AND MELINDA GATES FOUNDATION’s (BMGF) footprints are all over this story. I believe Gates thinks he can save the world through vaccines. He has pledged $10 billion to this project. For example, while the US contributes $893 million to the WHO budget, Gates contributes $902 million through the BMGF $531 million and Gates affiliated GAVI Alliance (Vaccines) $371 million. So what Gates wants, Gates gets. Gates may think he can heroically beat the COVID 19 pandemic through a vaccine. Problem ? It’s not ready. In the meantime, people sicken and die from Covid 19 and economic ruin destroys millions of lives. AND, there does exist an effective treatment, HCQ.
In the meantime a campaign of vilification and legal obstruction denies use of the proposed hydroxychloroquine HCQ cure successfully used by Dr Raoult in France and Dr Zelenko in New York.
Many think Gates’ interest is money. I think he has a hero complex. I believe what he wants is acclaim, applause, tearful gratitude. And power. An alpha male ape ego trip.
Back to his partners in crime. Dr Fauci’s NIAID agency and the NIH were partnered with the Wuhan virology lab as is the group led by the French Doctor Yves Levy (husband of Dr Buzyn who made HCQ unavailable in January 2020). The Virus may have escaped from this lab and the various Western governments are in panic mode to deny any association. Mid March Mike Pompeo spoke of an « exercise ». So what did he mean ?
The pro-vaccine crowd led and financed by Bill Gates appears responsible for blocking effective treatment for Covid 19 NOW in favor of a future Vaccine. How can this not be seen as a « crime against humanity. »
Do we really want to allow a very rich man, uneducated in science or medicine, to take control of Global Health ? If this debacle is any indication , it will no longer be the Medical Doctors who determine what is best for their patients, but the Gates Foundation and its Big Pharma allies.
Refer to the following links to back up the above.
https://www.sciencedirect.com/science/a ... 3920302179
In France, the combination hydroxychloroquine (HCQ) and azithromycin (AZ) is used in the treatment of COVID-19. Methods We retrospectively report on 1061 SARS-CoV-2 positive tested patients treated for at least three days with the following regimen: HCQ (200 mg three times daily for ten days) + AZ (500 mg on day 1 followed by 250 mg daily for the next four days).

Robert Kennedy accuses Bill Gates of Using …
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https://www.smobserved.com/story/2020/0 ... rt-kennedy...
From Robert F Kennedy Jr's Instagram post today: "Vaccines, for Bill Gates, are a strategic philanthropy that feed his many vaccine-related businesses (including Microsoft's ambition to control a global vac ID enterprise) and give him dictatorial control over global health policy-the …

• Gates Foundation Pledges $10 Billion For Vaccines : …
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https://www.npr.org/.../2010/01/gates_f ... 10_bi.html
29/01/2010 · Gates Foundation Pledges $10 Billion For Vaccines : Shots - Health News The Bill and Melinda Gates Foundation announced today that it plans to more then double its spending on vaccine …

Chloroquine is a potent inhibitor of SARS …
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https://www.ncbi.nlm.nih.gov/pubmed/16115318
22/08/2005 · CONCLUSION: Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.
• Cited by : 108
• Publish Year : 2005
• Author : Martin J Vincent, Eric Bergeron, Suzanne Benjannet, Bobbie R

https://www.sciencedirect.com/science/a ... 3920302179
In France, the combination hydroxychloroquine (HCQ) and azithromycin (AZ) is used in the treatment of COVID-19. Methods We retrospectively report on 1061 SARS-CoV-2 positive tested patients treated for at least three days with the following regimen: HCQ (200 mg three times daily for ten days) + AZ (500 mg on day 1 followed by 250 mg daily for the next four days).

EARLY DIAGNOSIS AND MANAGEMENT OF COVID-19 PATIENTS: A REAL-LIFE COHORT STUDY OF 3,737 PATIENTS, MARSEILLE, FRANCE
Accueil Early diagnosis and management of COVID-19 patients: a real-life cohort study of 3,737 patients, Marseille, France
27 mai 2020
COVID-IHU #15
Version 1 du 27 Mai 2020
Early diagnosis and management of COVID-19 patients: a real-life cohort study of 3,737 patients, Marseille, France
Abstract
Background:
In our institute in Marseille, France, we proposed early and massive screening for coronavirus disease 2019 (COVID-19). Hospitalization and early treatment with hydroxychloroquine and azithromycin (HCQ-AZ) was proposed for the positive cases.
Methods:
We retrospectively report the clinical management of 3,737 patients, including 3,054 (81.7%) treated with HCQ-AZ for at least three days and 683 (18.3%) patients treated with other methods (“others”). Outcomes were death, transfer to the intensive care unit (ICU), ≥ 10 days of hospitalization and viral shedding.
Results:
By testing 101,522 samples by polymerase chain reaction (PCR) from 65,993 individuals, we diagnosed 6,836 patients (10.4%), including 3,737 included in our cohort. The mean age was 45 (sd 17) years, 45% were male, and the fatality rate was 0.9%. We performed 2,065 low-dose computed tomography (CT) scans highlighting lung lesions in 581 of the 933 (62%) patients with minimal clinical symptoms (NEWS score = 0). A discrepancy between spontaneous dyspnoea, hypoxemia and lung lesions was observed. Clinical factors (age, comorbidities, NEWS-2 score), biological factors (lymphopenia; eosinopenia; decrease in blood zinc; and increase in D-dimers, lactate dehydrogenase (LDH), creatinine phosphokinase (CPK), and c-reactive protein (CRP)) and moderate and severe lesions detected in low-dose CT scans were associated with poor clinical outcome. Treatment with HCQ-AZ was associated with a decreased risk of transfer to the ICU or death (HR 0.19 0.12-0.29), decreased risk of hospitalization ≥10 days (odds ratios 95% CI 0.37 0.26-0.51) and shorter duration of viral shedding (time to negative PCR: HR 1.27 1.16-1.39). QTc prolongation (>60 ms) was observed in 25 patients (0.67%) leading to the cessation of treatment in 3 cases. No cases of torsade de pointe or sudden death were observed.
Conclusion
Early diagnosis, early isolation and early treatment with at least 3 days of HCQ-AZ result in a significantly better clinical outcome and contagiosity in patients with COVID-19 than other treatments. Long-term follow-up to screen for fibrosis will be the next challenge in the management of COVID-19.

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Re: Coronavirus (COVID-19) News

Post by NHE » Sun Jun 21, 2020 9:00 pm

Flushing the Toilet May Fling Coronavirus Aerosols All Over
A new study shows how turbulence from a toilet bowl can create a large plume that is potentially infectious to a bathroom’s next visitor.

https://www.nytimes.com/2020/06/16/heal ... shing.html

Here’s one more behavior to be hyper-aware of in order to prevent coronavirus transmission: what you do after you use the toilet.

Scientists have found that in addition to clearing out whatever business you’ve left behind, flushing a toilet can generate a cloud of aerosol droplets that rises nearly three feet. Those droplets may linger in the air long enough to be inhaled by a shared toilet’s next user, or land on surfaces in the bathroom.

This toilet plume isn’t just gross. In simulations, it can carry infectious coronavirus particles that are already present in the surrounding air or recently shed in a person’s stool. The research, published Tuesday in the journal Physics of Fluids, adds to growing evidence that the coronavirus can be passed not only through respiratory droplets, but through virus-laden feces, too.

And while it remains unknown whether public or shared toilets are a common point of transmission of the virus, the research highlights the need during a pandemic to rethink some of the common spaces people share.

“The aerosols generated by toilets are something that we’ve kind of known about for a while, but many people have taken for granted,” said Joshua L. Santarpia, a professor of pathology and microbiology at the University of Nebraska Medical Center who was not involved in the research. “This study adds a lot of the evidence that everyone needs in order to take better action.”

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Re: Coronavirus (COVID-19) News

Post by NHE » Tue Jun 23, 2020 7:47 am

Asymptomatic covid19 patients experience lung damage detected via CT scan.

We Still Don't Fully Understand The Label 'Asymptomatic'
June 23, 202010:31 AM ET

https://www.npr.org/sections/goatsandso ... ymptomatic

Even if someone is infected by the novel coronavirus and remains asymptomatic — free of coughing, fever, fatigue and other common signs of infection, that doesn't mean the coronavirus isn't taking a toll. The virus can still be causing mild — although, likely reversible — harm to their lungs.

A new paper in Nature Medicine, published June 18, documents the clinical patterns of asymptomatic infections. It finds that many of the people studied developed signs of minor lung inflammation — akin to walking pneumonia — while exhibiting no other symptoms of coronavirus.

The study shows that being asymptomatic doesn't always mean that no damage has occurred in someone's body; follow-up studies will help researchers assess for potential long-term impacts. It also demonstrates that the intense scrutiny applied to novel coronavirus infections could shed light on how other respiratory diseases operate: asymptomatic carriers of flu or common cold viruses are not studied much, so it's currently unclear whether the documented inflammation is a typical immune response or specific to the novel coronavirus.

The percentage of people with asymptomatic infections is unclear. "Estimates suggest that anywhere between 6% and 41% of the population may be infected but not have symptoms," Maria Van Kerkhove, a top World Health Organization official, said June 9.

Asymptomatic coronavirus carriers are hard to find and study — because people usually get tested for coronavirus only if they think they may have it. And some people who appear asymptomatic at first do later develop classic symptoms such high temperatures, fatigue and difficulty breathing.

The Nature paper analyzes 37 asymptomatic cases, found through the contact tracing and testing efforts of the Wanzhou District Centers for Disease Control and Prevention in central China, which screened 2,088 close contacts of coronavirus patients from February through early April.

The asymptomatic patients were hospitalized for observation. 57% showed lung abnormalities on a CT scan, a sensitive imaging technique that produces a three-dimensional picture of the lungs. Some showed "striped shadows," while others presented with "ground-glass opacities" — clear signs of inflammation in the lungs.

"To find so many asymptomatic patients with such significant changes on CT's is quite surprising," says Dr. Alvin Ing, a professor of respiratory medicine at Macquarie University who was not involved with the study. It shows that even people with no outward signs of infection can be experiencing some temporary damage to their lungs. It feeds into a pattern he's seen in treating COVID-19 patients: "The symptoms underestimate the severity of the disease." In other words, the coronavirus is often taxing a person's body more severely than their symptoms — or lack thereof — suggest.

The findings are consistent with several studies following asymptomatic patients in China, which have found that many can develop lesions in the lungs despite having no outward symptoms, says Dr. Jennifer Taylor-Cousar, a pulmonologist at National Jewish Health in Denver not involved with the paper. "It probably is, at least in this disease, pretty common," she says.

Doctors in New York have seen similar patterns. Dr. Jorge Mercado, a pulmonologist and critical care doctor at NYU Langone Hospital-Brooklyn who is not affiliated with the study, says he's seen many instances where a patient has come to the hospital for a non-COVID-related issue and tested positive for the coronavirus. "Those patients evolved into what this paper illustrates, which is [their coronavirus infections] causing pneumonia, causing inflammatory changes," he says.

Still, Taylor-Cousar cautions that researchers are studying the new coronavirus more intensively than they've studied other respiratory ailments. "Usually if someone is asymptomatic [with a common cold or flu virus], we would never even see them at all," she says, "and we would never think to get a CT scan on them." So there's no comparable data to say whether the lung abnormalities are specific to asymptomatic coronavirus carriers, or common among respiratory viruses.

The patterns of lung disease seen on the CT scan can be caused by several factors. "It can be a little bit of fluid in the lungs, sometimes a little blood in a lung or sometimes just a small area of inflammation in the lung," says Dr. Neil Schluger, chief of pulmonary, allergy and critical care medicine at the Columbia University Medical Center. "When I look at these images, I see what to me looks like small areas of inflammation that we see with many kinds of lung infections."

For asymptomatic cases with mild lung inflammation and no other signs of illness, pulmonologists say they're likely to kick the infection quickly and see no lasting lung damage.

"I suspect that, if you followed up with these asymptomatic people in several months, most of their CT scans would be completely normal unless they were known to later develop symptoms," says Taylor-Cousar.

In the midst of an infection, however, doctors can't predict how an individual's case will progress. "There's no way to know who is going to stop with an asymptomatic infection and likely recover completely and who is likely to go on to more severe infection," says Schluger.

The Nature study also found pieces of the coronavirus in swab samples from asymptomatic patients for an average of 19 days — five days longer than a control group of mildly symptomatic patients. While it doesn't necessarily mean asymptomatic people are infectious the whole time, it does suggest that they're capable of spreading the virus to others at some point in their infections, says Schluger. "As we reopen society, that's why it's so important for people who are going out to wear a mask," he says.

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MS x COVID characteristics and outcomes (Jun 26)

Post by jimmylegs » Sun Jun 28, 2020 2:06 am

Clinical Characteristics and Outcomes in Patients With Coronavirus Disease 2019 and Multiple Sclerosis (Jun 26)
https://pubmed.ncbi.nlm.nih.gov/32589189/

"...Conclusions and relevance: In this registry-based cohort study of patients with MS, age, EDSS, and obesity were independent risk factors for severe COVID-19; there was no association found between DMTs exposure and COVID-19 severity. The identification of these risk factors should provide the rationale for an individual strategy regarding clinical management of patients with MS during the COVID-19 pandemic."
https://www.who.int/news-room/q-a-detail/q-a-coronaviruses

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pursue optimal self care, with or without a diagnosis.

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Updated global advice (Jul 1)

Post by jimmylegs » Sat Jul 04, 2020 6:43 am

The coronavirus and MS – updated global advice (Jul 1)
https://www.msif.org/news/2020/02/10/th ... d-to-know/
https://www.who.int/news-room/q-a-detail/q-a-coronaviruses

take control of your own health.
pursue optimal self care, with or without a diagnosis.

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Re: Coronavirus (COVID-19): What You Need To Know

Post by Petr75 » Tue Jul 07, 2020 11:04 am

2020 Jun 19
Laboratory of Microbiology and Virology, Università Vita-Salute San Raffaele, Milan, Italy
Interferon-β 1a Inhibits SARS-CoV-2 in Vitro When Administered After Virus Infection
https://pubmed.ncbi.nlm.nih.gov/32559285/

Abstract

The ongoing COVID-19 pandemic has forced the clinical and scientific community to try drug repurposing of existing antiviral agents as a quick option against SARS-CoV-2. Under this scenario, the interferon-β 1a (IFN-β 1a) whose antiviral potential is already known, and is a drug currently used in the clinical management of multiple sclerosis, may represent as a potential candidate. In this report, we demonstrate that IFN-β 1a was highly effective in inhibiting in vitro SARS-CoV-2 replication at clinically achievable concentration when administered after virus infection.

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Re: Coronavirus (COVID-19): What You Need To Know

Post by vesta » Wed Jul 08, 2020 10:52 am

See also:

A Review of SARS-CoV-2 and the Ongoing Clinical Trials.
Tu YF, Chien CS, Yarmishyn AA, Lin YY, Luo YH, Lin YT, Lai WY, Yang DM, Chou SJ, Yang YP, Wang ML, Chiou SH.
Int J Mol Sci. 2020 Apr 10;21(7):2657. doi: 10.3390/ijms21072657.
PMID: 32290293 Free PMC article.

"The initial clinical studies revealed the promising therapeutic potential of several of such drugs, including favipiravir, a broad-spectrum antiviral drug that interferes with the viral replication, and hydroxychloroquine, the repurposed antimalarial drug that interferes with the virus endosomal entry pathway. We speculate that the current pandemic emergency will be a trigger for more systematic drug repurposing design approaches based on big data analysis."

Best, Vesta

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Re: Coronavirus (COVID-19): What You Need To Know

Post by Petr75 » Fri Jul 31, 2020 11:51 pm

2020 Jul 9
From the NYU Langone Multiple Sclerosis Comprehensive Care Center, New York, NY; and Cohen's Children Medical Center Northwell Health (C.F.-C.), Lake Success, NY
COVID-19 outcomes in MS: Observational study of early experience from NYU Multiple Sclerosis Comprehensive Care Center
https://pubmed.ncbi.nlm.nih.gov/32646885/


Abstract

Objective: To report outcomes on patients with multiple sclerosis (MS) and related disorders with coronavirus disease 2019 (COVID-19) illness.

Methods: From March 16 to April 30, 2020, patients with MS or related disorders at NYU Langone MS Comprehensive Care Center were identified with laboratory-confirmed or suspected COVID-19. The diagnosis was established using a standardized questionnaire or by review of in-patient hospital records.

Results: We identified 76 patients (55 with relapsing MS, of which 9 had pediatric onset; 17 with progressive MS; and 4 with related disorders). Thirty-seven underwent PCR testing and were confirmed positive. Of the entire group, 64 (84%) patients were on disease-modifying therapy (DMT) including anti-CD20 therapies (n = 34, 44.7%) and sphingosine-1-phosphate receptor modulators (n = 10, 13.5%). The most common COVID-19 symptoms were fever and cough, but 21.1% of patients had neurologic symptom recrudescence preceding or coinciding with the infection. A total of 18 (23.7%) were hospitalized; 8 (10.5%) had COVID-19 critical illness or related death. Features more common among those hospitalized or with critical illness or death were older age, presence of comorbidities, progressive disease, and a nonambulatory status. No DMT class was associated with an increased risk of hospitalization or fatal outcome.

Conclusions: Most patients with MS with COVID-19 do not require hospitalization despite being on DMTs. Factors associated with critical illness were similar to the general at-risk patient population. DMT use did not emerge as a predictor of poor COVID-19 outcome in this preliminary sample.

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Re: Coronavirus (COVID-19): What You Need To Know

Post by NHE » Sat Aug 01, 2020 1:21 am

One Man's COVID-19 Death Raises The Worst Fears Of Many People With Disabilities
July 31, 2020 3:29 PM ET

https://www.npr.org/2020/07/31/89688226 ... sabilities

What Melissa Hickson says happened to her husband — and what the hospital says — are in conflict.

But this much is for sure: Michael Hickson, a 46-year old quadriplegic who'd contracted COVID-19, died at St. David's South Austin Medical Center in Austin, Texas, on June 11 after the hospital ended treatment for him and moved him from the intensive care unit to hospice care.

Melissa Hickson says her husband was denied potentially lifesaving treatment because doctors at the hospital made a decision based on their biases that, because of his disabilities, Michael Hickson had a low quality of life.

The hospital says it acted based on the man's dire medical prognosis and that it would have been pointless and cruel to give him invasive treatment.

Michael Hickson's death has become a cause among many with disabilities, an emblem of a medical system that they believe views their lives as having less value, even before a pandemic put doctors and hospitals under stress.

And now Hickson's death may get the scrutiny of a federal civil rights office.

ADAPT of Texas, a disability rights group in Austin, sent a complaint on July 24 to the federal Office for Civil Rights at the Department of Health and Human Services. And on Friday, the National Council on Independent Living filed a similar complaint to ask the Office for Civil Rights to open an investigation into Hickson's death.

"In Mr. Hickson's case, the issue is not abstract," the complaint says. "The treating professional for Mr. Hickson made a discriminatory determination that, due to his disabilities, Mr. Hickson's life would not be supported."

In addition to those formal complaints, two members of the U.S. House of Representatives from Texas expressed alarm. Rep. Chip Roy, a Republican, called the circumstances around Hickson's death "highly troubling." And Rep. Joaquin Castro, a Democrat, said Hickson's death "should be immediately investigated."

Since the start of the pandemic, the federal civil rights office has kept an eye on health care rationing. Specifically, it has warned states, doctors and hospitals that they can't place elderly and disabled people at the back of the line for care for COVID-19.

"We're concerned that stereotypes about what life is like living with a disability can be improperly used to exclude people from needed care," said Roger Severino, the Office for Civil Rights director, on March 28 as he announced guidelines for states and medical providers.

To do so, he warned, would violate laws — including the Americans with Disabilities Act and the Affordable Care Act — that guarantee the disabled and older people will not face discrimination when they need medical care.

.....

On June 5, Hickson went to see her husband in the ICU at St. David's South Austin Medical Center.

Michael Hickson was a quadriplegic who'd been diagnosed with COVID-19. Now he had pneumonia. A BiPap machine, a kind of ventilator that people often use in their own homes, was pushing air into his lungs to help him breathe.

Through the mask, he answered her questions with short answers. Would you like me to get you a Long Island iced tea, she joked. Yes, he said with a smile. Will you pray with me? Yes.

She asked him "to keep it in your mind: You will live and not die. You will live." She asked him to repeat the words with her and she saw, under the mask of the breathing device, his lips move as he repeated it with her.

She called the kids on the phone — their five teenage children — for a FaceTime conversation. They told their Dad what they were up to. The 16-year-old was excited she was going to get her driver's license.

.....

That day at St. David's hospital, on June 5, the medical staff had something to tell Melissa Hickson. They were going to stop treating her husband. And move him from the ICU to hospice care.

In the hallway, Hickson found the doctor. She asked why. And she recorded their conversation.

The recording is hard to hear, the doctor's voice a bit distant. But he tells Hickson: "The decision is: Do we want to be extremely aggressive with his care or do we feel like this would be futile?"

And then he adds: "As of right now, his quality of life — he doesn't have much of one."

Hickson challenges the doctor. "What do you mean?" she asks. "Because he's paralyzed with a brain injury, he doesn't have quality of life?"

"Correct," the doctor replies.

After a while, the doctor gives a different explanation: If we have to intubate him — put him on a more powerful ventilator — in his weakened condition, he's not going to survive.

That didn't make sense to Melissa Hickson. The hospital wasn't overwhelmed with COVID-19 patients. It didn't need to ration care. Her husband had dealt with pneumonia before, and other hospitals had successfully treated it.

Listen to the recorded conversation between the doctor and Melissa Hickson. https://www.youtube.com/watch?v=jq-_gtjnzZg

[continued]

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Re: Coronavirus (COVID-19): What You Need To Know

Post by vesta » Mon Aug 03, 2020 2:46 am

"One Man's COVID-19 Death Raises The Worst Fears Of Many People With Disabilities
July 31, 2020 3:29 PM ET

https://www.npr.org/2020/07/31/89688226 ... sabilities"

One must get treated within days of symptoms to avoid hospitalization, and contrary to current propaganda, such treatment exists.

"THE COVID 19 VACCINE : A SORDID TALE
My French Country Doctor categorically refuses to prescribe Hydroxychloroquine to treat early symptoms of COVID 19. I don’t believe she is personally corrupted by Big Pharma (in this case Gilead, producer of Remdesivir) or the Vaccine crowd linked to WHO and Bill Gates. But she lives in fear of the French Medical Authorities who ARE. How else can one understand the French government ban on HCQ ? It is frightening to think that a medication sold over the counter like aspirin for 70 years has suddenly become unavailable because it is cheap and therefore a threat to Big Pharma’s profit plans. How else can one understand this scandal ?
It’s not the Science. In 2005 studies revealed that HCQ reduced the viral load of the Corona virus. Dr Raoult in Jan 2020, optimistically declared that this Corona virus COVID 19 could be easily, and cheaply, treated.. Late March 2020 Dr Zelenko wrote an open letter to Pres Trump recommending his ongoing successful outpatient treatment of Covid 19. May 28, 2020 Dr. Harvey A. Risch of Yale confirmed the effective outpatient use of HCQ during the first phase of the disease. He hopes to complete the Yale study of HCQ by September, 2020…
So why is Dr Fauci, the WHO, President Macron, and the French Medical authorities refusing to endorse this effective treatment ? Why are they lying about it Why do I consider this suppression of HCQ to be a sordid tale ? Why is the treatment belittled, discredited, mocked vilified by the Medical « Authorities, the MSM and its handlers ?
Because HCQ is inexpensive and it works to heal during the respiratory Phase I of the COVID 19 disease and prevents Phase 2 hospitalization and Phase 3 death. Not only does it prevent serious health complications after recovery, it saves millions in unspent hospital costs. Why are budget conscious governments squandering fortunes ? And further, if there exists a recognized effective drug treatment, a Vaccine would be unnecessary AND the economy need not be shutdown.
Of course in order to work the HCQ AZ ZINC tri-therapy has to be administered within days of symptoms. The health care system needs to be organized and responsive. The USA medical system would need to be mobilized in an unprecedented way. Rejecting the HCQ solution is an easy way to avoid recognizing the disaster of a privatized health care system.

For dull discussion see https://www.mscureenigmas.net/

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jimmylegs
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updated global advice (Aug 3)

Post by jimmylegs » Mon Aug 03, 2020 5:01 am

Global COVID-19 advice for people with MS
https://www.msif.org/news/2020/02/10/th ... d-to-know/

" ... National lockdown measures in place in many parts of the world might be relaxed in the coming weeks and months. Until our understanding of the coronavirus improves, people with MS in these higher risk groups and their caregivers should continue to follow the advice above to reduce their risk of contracting COVID-19."

i consider myself lucky to have the capacity to continue my day to day routine as if i am in phase 1 lockdown, or next thing to it. there are only a handful of active cases in my community, and i'm happy to help keep it that way!
https://www.who.int/news-room/q-a-detail/q-a-coronaviruses

take control of your own health.
pursue optimal self care, with or without a diagnosis.

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Re: Coronavirus (COVID-19): What You Need To Know

Post by NHE » Mon Aug 03, 2020 1:09 pm

NHE wrote:
Sat Aug 01, 2020 1:21 am
One Man's COVID-19 Death Raises The Worst Fears Of Many People With Disabilities
July 31, 2020 3:29 PM ET

https://www.npr.org/2020/07/31/89688226 ... sabilities

What Melissa Hickson says happened to her husband — and what the hospital says — are in conflict.

But this much is for sure: Michael Hickson, a 46-year old quadriplegic who'd contracted COVID-19, died at St. David's South Austin Medical Center in Austin, Texas, on June 11 after the hospital ended treatment for him and moved him from the intensive care unit to hospice care.

But if you're a nerdily cute woman in her 20's, then you might just get a lung transplant.

First COVID-19 double-lung transplant patient goes home
https://www.livescience.com/double-lung ... -home.html

The first COVID-19 patient in the U.S. to receive a double-lung transplant was discharged from the hospital this week, according to news reports.

After the coronavirus inflicted irreversible damage to her lungs, 28-year-old Mayra Ramirez underwent the transplant on June 5, Live Science previously reported. To qualify for the procedure, she first had to test negative for the virus, as transplant patients must take immune-suppressing drugs following the surgery. The drugs prevent the body from rejecting the new organ, but hobble the immune system's ability to fight off an active infection.

"Once Mayra's body cleared the virus, it became obvious that the lung damage wasn't going to heal, and we needed to list her for a lung transplant," Dr. Beth Malsin, a pulmonary and critical care specialist at Northwestern Memorial Hospital, said in a statement. Ramirez received her new lungs two days later.

Ramirez woke up following the 10-hour operation with "all these tubes" coming out of her — "I just couldn't recognize my own body," she told The New York Times. Prior to the surgery, Ramirez spent six weeks in the intensive care unit (ICU) on a ventilator and an extracorporeal membrane oxygenation (ECMO) machine, which pumps oxygenated blood through the body when the heart and lungs cannot do so alone.

"I don't remember anything during my six weeks in the COVID ICU. When I finally woke up, it was the middle of June and I had no idea why I was in a hospital bed," Ramirez said in the statement from Northwestern. When she finally awoke, her nurses asked if she knew the date and Ramirez guessed that it was early May, according to the Times. She was able to return home on July 29.


[Two months in the hospital and a lung transplant. That's going to be some bill.]

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Re: Coronavirus (COVID-19): What You Need To Know

Post by PeterX » Mon Aug 24, 2020 12:53 pm

I, too, watched the panic surrounding COVID-19 and noticed that no one mentions Amantadine as a cure for this virus. Coincidentally, I found a few interesting articles that talk about it.
Patients with MS often take Amantadine to fight fatigue. I personally have been using it for a long time, almost 20 years.
It is true that I have not had any problems with the COVID-19 virus so far, so I wonder if anyone else has had similar experiences with Amantadine.

https://www.sciencedirect.com/science/a ... 772030654X
https://www.sciencedirect.com/science/a ... via%3Dihub
https://www.researchgate.net/publicatio ... t_COVID-19
https://multiple-sclerosis-research.org ... /#comments
https://www.msard-journal.com/article/S ... X/fulltext

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Debunking COVID-19 myths

Post by jimmylegs » Wed Aug 26, 2020 12:38 pm

Debunking COVID-19 (coronavirus) myths
https://www.mayoclinic.org/diseases-con ... t-20485720

my beloved immune system-boosting essential nutrients, maligned!
ok well not really. either way, i accept that i can't use my supplements as an alternative to good distancing precautions and personal hygiene :)
https://www.who.int/news-room/q-a-detail/q-a-coronaviruses

take control of your own health.
pursue optimal self care, with or without a diagnosis.

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