How many have noticed results on twice daily dosing?

A board to discuss Low Dose Naltrexone (LDN) as a treatment for Multiple Sclerosis
Post Reply
zjac020
Family Elder
Posts: 196
Joined: 5 years ago

How many have noticed results on twice daily dosing?

Post by zjac020 » 6 months ago

Just wondering. Dont really notice anything with daily dosing at night, wondering if anyone has benefitted from twice daily.

I weigh 65kgs and usually take 4mg.

Thanks,

AntonioBR
Family Elder
Posts: 607
Joined: 3 years ago

Re: How many have noticed results on twice daily dosing?

Post by AntonioBR » 5 months ago

Hi zjac020,

How long have you been using LDN?

Have you tried a 4,5mg or 3mg dose?

Why do you take a dose of 4mg and not 4,5mg?


I'm asking because with LDN things works a bit differently.

It does not mean that as higher the dose better will be the results.

Sometimes a low dose will stimulate even more the immune system. Dr. Bihari noticed that for some patients 3mg worked better than 4,5mg and he also noticed that doses higher than 4,5mg had not the same good immunomodulatory effects that the low doses.

So, a twice-daily dose would be probably counterproductive based on LDN.


My brother has MS and he takes 4,5mg every day at night. He noticed good results.

My mother has Rheumatoid Arthritis and she takes 3mg every day at night. She also noticed good results.

I take 3mg for prevention for autoimmune diseases and cancer. (as many doctors that prescribe LDN also take it for prevention)

AntonioBR
Family Elder
Posts: 607
Joined: 3 years ago

Re: How many have noticed results on twice daily dosing?

Post by AntonioBR » 5 months ago

Otherwise Dr. Zagon use twice daily LDN doses in some people


"Can LDN be taken twice a day?

According to Dr. Zagon's studies the optimal daily dose of LDN is between 2.5 and 10mg. It is conceivable that some individuals, depending on their metabolism, would benefit from taking two doses daily of 3mg or 4.5mg, 12 hours apart, and in fact this has been reported by some people."

Post Reply
  • Similar Topics
    Replies
    Views
    Last post
  • Changing natalizumab dosing frequency reduced risk for PML
    by MSUK » 11 months ago » in Tysabri (Antegren or Natalizumab)
    1 Replies
    1242 Views
    Last post by ElliotB
    11 months ago
  • blood test results
    by zen2010 » 1 year ago » in General Discussion
    44 Replies
    2379 Views
    Last post by jimmylegs
    4 months ago
  • Blood test results
    by SARABAND » 11 months ago » in Regimens
    5 Replies
    1299 Views
    Last post by jimmylegs
    11 months ago
  • On edge waiting for MRI results
    by CeliaV » 4 months ago » in Undiagnosed
    3 Replies
    659 Views
    Last post by jimmylegs
    4 months ago
  • MRI results waiting for my neurologist to get back in town.
    by evecronin » 5 months ago » in Undiagnosed
    6 Replies
    733 Views
    Last post by evecronin
    5 months ago