2/2007: First (and only) MS-exacerbation, started with Rebif
3/2008: First round of Campath (high dose; off-label)
5/2009-1/2010: Pregnancy (we had some little troubles to conceive), delivered a perfectly healthy baby
3/2010: Second round of Campath (high dose; off-label)
7/2010: Early miscarriage (surprise pregnancy); no chromosomal abnormalities found (had a D&C)
I went to work fine, came home at night still feeling perfectly fine only to discover my legs were covered in bruises and I had gingival bleeds... I knew what it meant so straight to the ER, my platelets were only at 7k, they started steroids but the following morning I had only 3k. Now getting IVIg treatment.
And still feeling fine!!
They say I should be over it with 4 days of IVIg, and it should not return or become chronic afterwards. If I would get ITP again, they can treat it just the same way, even during pregnancy... not that I would take that decision lightly, I have had my wake-up call now and really don't wan't to die...
However, I am thinking about the miscarriage 3 months ago and potential immune problems... very interesting now, considering one of the treatments for immune-related fertility problems (cfr Dr Beer) is IVIg, the same treatment as I'm getting now for my ITP!
How are you now?
I don't know @ Dr. Beer or fertility autoimmune issues. Are they campath, or ms related...or a thought on causes of miscarriage being that momma's immune system doesn't recognize baby?
(2 high dose campath- genzyme study treatments, 2 ccsvi liberations, my body is still fighting something affecting my gait & co-ordination!)
One week after treatment I had a count of 234k, 6 weeks after treatment, when all the IVIg should have been out of my body, I even had 394k. Which is very very very good!
According to my hematologist, it won't be anything chronic, not "idiopathic" but entirely campath-related. The campath was still in my body 6 months after campath-treatment, and even now there could still be traces left.
I'm staying really vigilant about all those things, but the future is looking bright again. I even have "permission" to get pregnant again
(the fertility autoimmune issues according to Dr Beer just "are", like ms just "is"... indeed, the immune system does not recognize the baby which leads to destruction... but it is not known whether campath or ms or anything else might be a cause)
And fortunately still no flare-ups or progression from ms
There is no guarantee whatsoever that the ITP won't return. But they think there is not any "classic" auto-immune ITP going on right now.
After all, I can live with that kind of uncertainty. It's almost the same as MS-uncertainty, but I think it's even better. If I would discover another ITP-flare-up soon enough, it can be treated very well in my case (up untill now), and it does not lead to disability. If I would be too late, I would be either dead or have a stroke, and than it's just game over...
(but I hate MS more!!!! Still no flare-ups however....)