OxyPharma Announces Selection of MS Drug

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OxyPharma Announces Selection of MS Drug

Post by LindaR » Fri Apr 08, 2005 6:19 am

Found this on the internet.

OxyPharma Announces Selection of Multiple Sclerosis (MS) Drug Development Candidate

STOCKHOLM, Sweden, April 5, 2005--Swedish drug development company OxyPharma has selected a candidate drug (CD) for the treatment of multiple sclerosis (MS) from its autoimmune diseases drug discovery program. The selected compound, Rob 895, is now ready to go into a full-scale pre-clinical program.

Rob 895 has been developed from OxyPharma's patented lead compound B-220, from which OxyPharma has developed several analogue substances, which in animal studies have shown very promising results for the treatment of both MS and rheumatoid arthritis (RA).

Based on the successful completion of the pre-clinical program for Rob 895, OxyPharma intends to submit a regulatory filing for the initiation of first-time-in-human clinical studies.

The selected compound (Rob 895) is the second drug candidate arising from OxyPharma's drug discovery program. Last year, OxyPharma selected Rob 803 as its candidate drug for the treatment of RA. OxyPharma is currently conducting toxicological studies of Rob 803 and intends to start Phase IIa clinical studies of the compound in early 2006.

Additional research has demonstrated Rob 895 to be a more attractive drug candidate than the lead compound for pharmaceutical development due to properties that include improved potency, tolerability, pharmacokinetics and pharmaceutics.

MS is a chronic, inflammatory condition to the nervous system afflicting approximately 2.5 million people worldwide. Most patients diagnosed with MS are between the ages of 30 and 50, and the disease has a medium duration of more than 30 years. The value of the MS market was USD 3.5bn in 2003, and is growing rapidly.

At present, there are no effective, safe and easily administrated drugs for the treatment of neither MS nor RA. Animal studies indicate that OxyPharma's small molecule substances can be effective, easy to administrate orally and may be produced at low cost compared to present alternatives for the treatment of both diseases.

About OxyPharma:

OxyPharma is a Swedish drug development company developing new drugs primarily for the treatment of Rheumatoid Arthritis (RA) and Multiple Sclerosis (MS). The development of the drugs are done in collaboration with e.g. the Karolinska Institute in Sweden and contract research organizations (CRO's) in England, Sweden and Israel. OxyPharma was founded in 2002 and is based in Stockholm, Sweden. The company's largest shareholder is innovator and entrepreneur Leif Lundblad. Ulf Björklund is OxyPharma's CEO.

OxyPharma is presently conducting a financing round of SEK 80-130m aimed at primarily European investors. The objective is to secure the midterm need for operative capital to further develop OxyPharma's RA and MS drugs (e.g. by clinical studies).

For additional information please contact:

Ulf Björklund CEO, OxyPharma AB Phone: +46 8 726 17 02 or +46 70 667 04 40

Email: ulf.bjorklund@oxypharma.com


Peter Karaszi Press Officer, OxyPharma AB Phone: +27 21 439 8806 or +27 83 243 5797

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As far as I'm concerned...

Post by Outlawbiker » Fri Apr 08, 2005 9:26 am

Oral is always better in my book :wink:

God, I hate needles!

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Post by LindaR » Fri Apr 08, 2005 11:21 am

I agree with you to G, oral is always better. Hate those pricks!

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Post by treez » Fri Apr 08, 2005 4:39 pm

Don't mind the pricks, just need effectiveness.

30-35% just doesn't cut it!


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Post by deehammer » Fri Apr 15, 2005 12:58 am

I agree with Treez, it gotta be really effective, but I'd also prefer oral to shots. I don't think that I'll ever get use to the shots and I've been doing this for 4 years.


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Re: OxyPharma Announces Selection of MS Drug

Post by HarryZ » Fri Apr 15, 2005 6:31 pm

At present, there are no effective, safe and easily administrated drugs for the treatment of neither MS nor RA.

Hmmm...I wonder what the CRAB drug companies would have to say about this statement by Oxypharma?!!! Not that I disagree with the comment but I'm sure it would ruffle a few feathers.


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