BTG Commences Phase IIa Study Of Pleneva For Multiple Sclerosis - Quick Facts
1/21/2010 2:51 AM ET
(RTTNews) - BTG Plc (BGC.L: News ) said it commenced dosing in a European multicentre Phase IIa study of Pleneva, a novel orally administered compound under development as a potential treatment for multiple sclerosis.
According to the company, the study, in 166 patients with the relapsing-remitting form of the disease, comprises an initial 24 week double-blind, placebo-controlled dosing period followed by a 24 week open-label extension. The primary endpoint of the study is a reduction in the number of new T1 gadolinium enhanced lesions on MRI at weeks 12, 16, 20 and 24 when compared to placebo.
Pleneva
- scoobyjude
- Family Elder
- Posts: 517
- Joined: Sat Feb 18, 2006 3:00 pm
- Location: suburb of Chicago, IL USA
- Contact:
Pleneva
Dxed Jan 2006. Sx since 2002. Rebif since March 2006. "When one door closes, another opens but we often look so long and so regretfully upon the closed door that we do not see the one which has opened for us." Alexander Graham Bell
- CureOrBust
- Family Elder
- Posts: 3374
- Joined: Wed Jul 27, 2005 2:00 pm
- Location: Sydney, Australia
http://www.btgplc.com/DevelopmentPipeli ... 00134.html
Now I'm interested.In a small single-centre, double-blind, placebo-controlled clinical pilot study, an experimental Pleneva™ prototype provided clinical benefits to patients with RRMS, including decreases in both relapse rate and EDSS scores, with additional benefits seen on pain and cognitive endpoints.
- Suchislife
- Getting to Know You...
- Posts: 10
- Joined: Mon Apr 25, 2011 2:00 pm
- Location: Havelock, NC
- Contact:
Do we know if this drug made it or not??? Is it in another phase?? I can see it has been awhile, but I am interested. I'm searching through the forum, but I can't seem to find it... Help if you can.
Thanks!
Thanks!
"If a man does not keep pace with his companions, perhaps it is because he marches to the beat of a different drummer. Let every man keep step to the music that he hears, however measured or far away." - Henry David Thoreau ~Audrey
Re: Pleneva
any update ? pleasescoobyjude wrote:BTG Commences Phase IIa Study Of Pleneva For Multiple Sclerosis - Quick Facts
1/21/2010 2:51 AM ET
(RTTNews) - BTG Plc (BGC.L: News ) said it commenced dosing in a European multicentre Phase IIa study of Pleneva, a novel orally administered compound under development as a potential treatment for multiple sclerosis
According to the company, the study, in 166 patients with the relapsing-remitting form of the disease, comprises an initial 24 week double-blind, placebo-controlled dosing period followed by a 24 week open-label extension. The primary endpoint of the study is a reduction in the number of new T1 gadolinium enhanced lesions on MRI at weeks 12, 16, 20 and 24 when compared to placebo.
Re: Pleneva
from the manufacturers web sitearabia wrote:any update ? please
BGC20-0134 (Pleneva™) did not meet its primary or secondary endpoints in a six-month double-blind placebo-controlled Phase IIa study in patients with relapsing remitting multiple sclerosis. Data from approximately 65% of patients who have completed an optional six-month open-label study extension will be analysed to determine if any treatment effects are evident at 12 months that were not found after 6 months.