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Re: klenner protocol

Posted: Wed Oct 31, 2018 3:34 am
by Kheuer
https://www.hindawi.com/journals/ppar/2009/853707/

Nicotinic Acid-Mediated Activation of Both Membrane and Nuclear Receptors towards Therapeutic Glucocorticoid Mimetics for Treating Multiple Sclerosis

I think Klennet was correct. Remember, he has an MS in Biochemistry and an MD

Re: klenner protocol

Posted: Sat Nov 03, 2018 4:42 am
by jimmylegs
the klenner protocol as i modified it for my use helped me more than anything else, up to a point. i had been vegan and desperately needed its nutrient dense approach, significantly including the protein.

doesn't mean that knowledge from the 70s is perfectly applicable today (eg protocol has nothing on d3 or details of relevant cofactors), and from my attempts to look into them, it by no means is the case that the protocol references cut the academic mustard - author's md, ms or not.

Re: klenner protocol

Posted: Mon May 25, 2020 11:28 am
by jimmylegs
with permission, bringing a PM conversation up front here :)
Klenner
Sent: Sun May 24, 2020 9:24 pm
Thank you in advance for reading this message.
I wonder if you could tell me what you took during your oral Klenner regimen.
I realize that there is no miracle pharmacopeia.
I am just looking into plausible things I can do to attempt to help my old man. H
PS - have any thoughts on Metformin or NAC?
Thank you for your time...
Re: Klenner
Sent: Mon May 25, 2020 9:14 am
From: jimmylegs
...
the short answer is that it's complicated.
if you want to follow up further we can discuss, but in that case i would likely want to take it out into the main forum, if that's acceptable on your end :) i would have questions for you there to help decide on the best way forward, if any :)
ok here are some preliminary questions.

1. before you exert time and energy, how likely is your dad to take on self care strategies like modified klenner or anything else, on his own behalf? (like the old joke says, that light bulb has to really *want* to change)

2. does dad have access to / interest in taking on the dietary approaches that over the long term, should underlie any short term therapeutic round of klenner's combo diet/supplement protocol?

3. would dad consider preparing/sharing a diet diary to help decide whether his personal status quo is a logical fit with the klenner approach?

in my case, as a chronic and ever more stringent ideological, misinformed, and supplement-averse vegan, several elements made a lot of sense. eg the high protein diet with 2-3 eggs for breakfast and the high intakes of B vitamins, esp b12.
in hindsight, i would realize later that even the high dose vitamin E in klenner probably played a part, because of my misinformed earlier tendency to avoid fat - even via vegan options like nuts and seeds.

looking back on it all ~15 yrs later, it is ever more clear to me that there are very good reasons why single protocols don't necessarily work for all. details, details, details! all fascinating afaic :D

i'll reiterate here too that although i do have an MSdx and genetically am in a higher risk group, i also have permanent damage (stocking glove neuropathy) which i associate with subacute combined degeneration of the spinal cord secondary to b12 deficiency, as distinct from concurrent MS. more about that here https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1831618/
there's no turning that around; i let it go too long. maybe one day some kind of spinal cord work could help, but for now i'm content to wait in line behind folks with more serious spinal cord problems.

re metformin or NAC, i have always worked with essential nutrients and so have nothing useful to contribute on those two.

final thought, nutrients cannot work alone. more than once, physiotherapy has played *the* key role in averting my problems whether those were 1. chronic pain unrelated to ms, or 2. visual disturbances after an infection x new brain lesion led to ... wait for it (scrolling through memory files) ... internuclear ophthalmoplegia. ms lit is not encouraging. luckily the traumatic brain injury lit was.

end rant ;) i hope there's something you can use in this reply!