Fish oil normalizes membrane fluidity and mitochondrial ATPase activity in RRMS

Discuss herbal therapies, vitamins and minerals, bee stings, etc. here
Post Reply
User avatar
NHE
Volunteer Moderator
Posts: 5527
Joined: Sat Nov 20, 2004 3:00 pm
Contact:

Fish oil normalizes membrane fluidity and mitochondrial ATPase activity in RRMS

Post by NHE » Thu Jan 30, 2020 3:31 am

Omega-3 fish oil normalizes membrane fluidity and mitochondrial ATPase activity in RRMS.

Effect of fish and olive oil on mitochondrial ATPase activity and membrane fluidity in patients with relapsing-remitting multiple sclerosis treated with interferon beta 1-b.
Nutr Hosp. 2018 Jan 12;35(1):162-168.
  • BACKGROUND: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system associated with increased oxidative stress (OS) and mitochondrial alterations. Fish oil consumption has neuroprotective, antioxidant and anti-inflammatory effects in patients with relapsing-recurrent MS (RR-MS).

    OBJECTIVE: To evaluate changes in the hydrolytic activity of ATP synthase and mitochondrial membrane fluidity in patients with RR-MS who receive fish oil or olive oil as a dietary supplement.

    METHODS: Clinical, controlled, randomized, double-blind trial. Patients consumed fish oil or olive oil for one year. The hydrolytic activity of ATPase and the fluidity of the mitochondrial membrane of platelets were quantified.

    RESULTS: In patients with RR-MS, a decrease in the fluidity of mitochondrial membranes and an increase in the hydrolytic activity of ATP synthase was observed in comparison with healthy controls. After 6 or 9 months of treatment with fish oil or olive oil, respectively, these values were normalized.

    CONCLUSION: The consumption of fish oil and olive oil increases the fluidity of the mitochondrial membranes and decreases the catabolic activity of ATP synthase in platelets from patients with RR-MS

Free full text.

Post Reply
  • Similar Topics
    Replies
    Views
    Last post

Return to “Natural Approach”