- Family Elder
- Posts: 2201
- Joined: Thu Jun 17, 2004 2:00 pm
- Location: Bedfordshire UK
The study evaluated approximately 200 patients and followed them for two years. Approximately half were given Minocycline and half were given a placebo. It was a controlled randomized study. The results of the study were recently published and showed that Minocycline group had a significantly better outcome than the placebo group, i.e. fewer people receiving Minocycline had a relapse or became definite MS patients than the people in the placebo group. Essentially, Minocycline proved as or more effective than the standard disease modifying drugs over a two year period. The cost of the Minocycline, however, can be as much as 95% less, and it has fewer side effects and risks.
Here is a link to a report of the study presentation at the Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) 2015: http://www.medscape.com/viewarticle/852565. (It you don't want to do the login, you can Google search "Minocycline, MS, Dosage" and you will see the same link but without the login requirement.) I don't know what journal the study was published in, but I am sure you can find it.
At a minimum, this study suggests that anyone with early MS should discuss Minocycline with their neurologist as a possible first treatment before starting the more expensive and risky standard MS drugs.