Rituximab kills auto reactive plasma B cells

A board to discuss the anticipated multiple sclerosis treatment Rituxan.
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Anonymoose
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Joined: Tue Oct 09, 2012 6:33 am

Rituximab kills auto reactive plasma B cells

Post by Anonymoose »

I was worried about the ebv infected plasma cells escaping rituxan because plasma cells don't usually express cd20. Looks like there is a chance rituxan might kill those buggers after all. :)

Rituximab specifically depletes short-lived autoreactive plasma cells in a mouse model of inflammatory arthritis
http://m.pnas.org/content/107/10/4658.full
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