Occam's Razor

[smokey]

Occam's razor (or Ockham's razor[1]) is the principle that "entities must not be multiplied beyond necessity" (entia non sunt multiplicanda praeter necessitatem). The popular interpretation of this principle is that the simplest explanation is usually the correct one...........

[cheerleader]

yup.
http://www.thisisms.com/ftopicp-85770-razor.html#85770

The problem with the EAE model, Bill, is that in order to create it, you need to inject a foreign antigen into the body...so the assumption is that some foreign matter enters the CNS and creates this reaction.

In encephalomyelitis (a differential for MS)- the reaction of inflammation and demyelination is created by a virus or vaccine.

Putnams' dogs developed an encephalitic reaction (inflammatory/demyelination) that looked just like MS WITHOUT introducing any foreign matter....simply by blocking the cerebral veins. Ockham's Razor.

Why do we continue to use a model which needs that extra step of foreign matter injection into the CNS of animals? I think it's because immunologists can "cure" EAE....but it takes a VASCULAR doctor to stop venous reflux and congestion. Venous doctors have never studied MS...until now.
cheer

[smokey]

Awwww, thought I might have been original.....never mind. Still a damn fine principle.

[cheerleader]

Awwww, thought I might have been original.....never mind. Still a damn fine principle.

Ockham and Zamboni are the originals
and I agree with you 100%, smokey-

[sbr487]

Occam's razor (or Ockham's razor[1]) is the principle that "entities must not be multiplied beyond necessity" (entia non sunt multiplicanda praeter necessitatem). The popular interpretation of this principle is that the simplest explanation is usually the correct one...........

This is especially true in case of MS since routine method of explaining MS has failed for such a long time. As they say, when everything fails, start all over again. Thats the damn thing the neuros are not capable of. They dont want to climb down from the castles they have build in air all over the years ...

[smokey]

Too true!

May Occam and Zamboni be eternally cited!

It's a privilege to be at the cutting edge.

[cah]

The naysayers always talk about "Zamboni's theory" in a way that suggests that he's on his own with this in order to make it look alien. But as we all know, he isn't. There's a bunch of specialists which not only have adopted the theory but actively contribute to it. We shouldn't talk about Zamboni alone.

Don't know if Occam was on his own, though...

[LR1234]

More and more top vascular specialists are coming on board so like you have said Zamboni is not a lone ranger, he is part of a growing army:)

I reckon by this time next year CCSVI will be recognised as a treatable condition in every country. I don't think it can ever be suppressed now, the banks have burst!!:)

[Cece]

I reckon by this time next year CCSVI will be recognised as a treatable condition in every country.

except the US and Canada....

[1eye]

I have at times tried to make a list of countries where Liberation is allowed:

Bulgaria
Italy
Germany
France
UK
US (if not in a trial. otherwise IRB footdrag)
Poland
Mexico
NOT CANADA
Kuwait
Jordan

any other? I can't remember them all.

Occam's -- A great shave, every time...

[ErikaSlovakia]

I have at times tried to make a list of countries where Liberation is allowed:

Bulgaria
Italy
Germany
France
UK
US (if not in a trial. otherwise IRB footdrag)
Poland
Mexico
NOT CANADA
Kuwait
Jordan

any other? I can't remember them all.

Occam's -- A great shave, every time...

- Slovakia - so far 8 procedures, they use stents, doctors are not sure yet but so far they "only" had to have permission from the hospital
- Czech Republic - 12 procedures - I do not have any other details
Erika

[PCakes]

costa rica
australia

[Cece]

Egypt, Costa Rica, India

[LR1234]

Serbia