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on serum magnesium, stents and adverse events

Posted: Wed Feb 06, 2019 9:23 am
by jimmylegs
  • Association between Low Serum Magnesium Level and Major Adverse Cardiac Events in Patients Treated with Drug-Eluting Stents for Acute Myocardial Infarction (2014) ... ne.0098971

    We investigated the association of serum magnesium (Mg) levels and major adverse cardiac events (MACEs) after drug-eluting stent (DES) implantation
    For patients with myocardial infarction, after adjusting for age, positive family history, smoking status, hypertension, hypercholesterolemia, and diabetes at baseline, the risk was 8.11-fold higher for patients with quartile 1 than 4 Mg level (95% confidence interval 1.7–38.75; P<0.01).
    Median serum Mg concentration at admission was 0.92 mmol/L (0.87–0.97 mmol/L). For further analysis, patients were divided into 4 groups by serum Mg quartile: quartile 1, <0.87 mmol/L; quartile 2, 0.87 to 0.91 mmol/L; quartile 3, 0.92 to 0.96 mmol/L; and quartile 4, >0.96 mmol/L.
    Low serum level of Mg may be an important predictor of MACEs with DES implantation for acute myocardial infarction. Further research into the effectiveness of Mg supplementation for these patients is warranted.
(if you are curious, the conversion factor for mag is 0.411. ie mmol/l result divided by 0.411 = mg/dl result)

so, q4 looks like the sweet spot (again). as usual however, all participants' levels are 'normal'...

<font=sarcastica>nothing to see here folks, serum magnesium is useless info</font>

Bioabsorbable Magnesium Stents

Posted: Sat Feb 09, 2019 1:30 pm
by jimmylegs
related info posted a few years back:


content excerpt:

Drug-Eluting Bioabsorbable Magnesium Stent (2004)

"In this article, we describe the first biodegradable stent based on a magnesium alloy that allows controlled corrosion with release to the vessel wall and the blood stream of a natural body component such as magnesium with beneficial antithrombotic, antiarrhythmic, and antiproliferative properties."