James Watson's discovery of DNA structure in 1953

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.
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1eye
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James Watson's discovery of DNA structure in 1953

Post by 1eye » Fri Oct 07, 2011 2:17 pm

In unix-land this technique would be called a "diff". It finds deletions from other DNA (like the parent's, in autism) by comparing one to another genome. In this TED talk, Watson talks about the discovery of DNA's structure, but when he goes on to talk about diseases it gets really interesting. They use a specialized chip to do the scanning. If we could do this for "MS" it would probably be very revealing.
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Re: James Watson's discovery of DNA structure in 1953

Post by sbr487 » Fri Oct 07, 2011 11:58 pm

1eye,

** I am not an expert but here is my take **

I have read some paper relating to genes and MS. Most of the current research assume the culprit is a malfunctioning immune system and then try to find the culprit genes (within the known genes that control the immune system). If CCSVI is true then you won't find anything wrong in the immune system, since nothing is inherently wrong there. So, as long as the starting point is incorrect, the issue likely to escape (remember starting point & local minimas, 1eye)

The second part of the problem is that difference between genes may or may NOT mean anything. For example, it is normal for genes to undergo mutation. Part of normal process. But every mutated gene need not cause a specific issue.

But yes, the current issue in doing exhaustive gene scanning is probably time. And if technology improves (like chips doing this task) then complete scanning might become routine ...

Some exciting times ahead ...
A new scientific truth does not triumph by convincing its opponents and making them see the light, but rather because its opponents eventually die and a new generation grows up that is familiar with it
- Max Planck

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Re: James Watson's discovery of DNA structure in 1953

Post by 1eye » Sat Oct 08, 2011 6:14 pm

it seems that cases where complete deletion is present are scannable with this chip...
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