MMSE is the mini mental state exam: https://en.wikipedia.org/wiki/Mini%E2%8 ... xaminationAnalysis of nicergoline in treating elderly chronic cerebrospinal venous insufficiency
(1. Department of Neurology, China Meitan General Hospital, Beijing
100028, China; 2. Department of Emergency, The First Affiliated Hospital of Henan University of Science and
Technology, Henan, Luoyang 471000, China)
Abstract 【Abstract】 Objective To investigate the clinical effect of nicergoline in treatment of elderly patients with
chronic cerebrospinal venous insufficiency.
Method Used random number table method to selected 162cases of elderly patients with chronic cerebrovascular venous insufficiency from July 2012 to July 2014 in
our hospital as research objects, they were divided into nicergoline group and routine group, 81 cases in each
group. Routine group patients were treated with conventional methods, on the basis of conventional treatment,
nicergoline group patients were treated with nicergoline. Clinical effects of the two groups were compared.
Result Before treatment, the index [color Doppler ultrasound detection of vertebral artery and middle cerebral
artery, the end diastolic velocity (Vd), peak systolic velocity (Vs), resistance index (RI), pulsatility index (PI)]
were not significant different (P > 0.05); 12 weeks after treatment, Vd, Vs, RI, PI of the two groups patients
were significantly improved than before treatment, the difference was significant (P < 0.05), and Vd, Vs, RI, PI
of nicergoline group patients were superior to control group, the difference was significant (P < 0.05). MMSE
scores of the two groups patients before treatment were not significant different (P > 0.05); after treatment,
MMSE scores of the two groups patients were significantly increased than before treatment (P < 0.05), and
MMSE scores of nicergoline group was (24.5±1.3) points, significantly higher than routine group [(22.9±1.5)
points], the difference was significant (P < 0.05). 12 weeks after treatment, total effective rate of nicergoline
group was 91.36%, significantly higher than routine group (76.54%), the difference was significant (P < 0.05).
Conclusion Nicergoline can improve patients with elderly chronic cerebrospinal venous insufficiency clinical
symptoms and brain blood flows, and can significantly improve the clinical treatment effect.
Nicergoline is prescribed for migraines among other things https://en.wikipedia.org/wiki/Nicergoline
Could be a good complement to ccsvi angioplasty
Xièxiè (thank you) to the researchers