Identifying Microvascular Differences in Multiple Sclerosis via Optical Coherence Tomography Angiography (OCT-A)
https://iovs.arvojournals.org/article.a ... id=2768711
Conclusions :
Curated OCT-A and macular vessel density data suggests microvascular differences in MS patient groups compared to healthy controls. This is indicative of a potential relationship between ophthalmic microvascular changes and MS severity.
Further statistical analysis will help to highlight the significance of these early findings. Preliminary data further suggests that specific regions of the macula may be particularly affected by MS.
Future research investigating microvascular biomarkers on OCT-A imaging may enable ophthalmologists and neurologists to better care for MS patients and preserve eye function.
vascular problems in the MS eyes
Retinal vascular changes in Multiple Sclerosis
Characterization of Retinal vascular changes in Multiple Sclerosis using Adaptive Optics and OCTA
https://iovs.arvojournals.org/article.a ... id=2768856
Conclusions
AO-SLO (Adaptive optics scanning laser ophthalmoscopy) demonstrates focal retinal vessel changes in living human MS eyes without history of optic neuritis. These may correspond with microscopic retinal vascular changes previously observed in post-mortem samples.
Periphlebitis, a qualitative retinal vascular changes on clinical exam and retinal vessel density (RVD) decreased on OCTA have been observed in people with multiple sclerosis (MS). Focal microscopic changes in both inflamed and non-inflamed retinal vessels have been observed postmortem.
Adaptive optics scanning laser ophthalmoscopy (AO-SLO) facilitates viewing of the in vivo human retina with microscopic resolution and has not been widely applied in MS.
https://iovs.arvojournals.org/article.a ... id=2768856
Conclusions
AO-SLO (Adaptive optics scanning laser ophthalmoscopy) demonstrates focal retinal vessel changes in living human MS eyes without history of optic neuritis. These may correspond with microscopic retinal vascular changes previously observed in post-mortem samples.
Periphlebitis, a qualitative retinal vascular changes on clinical exam and retinal vessel density (RVD) decreased on OCTA have been observed in people with multiple sclerosis (MS). Focal microscopic changes in both inflamed and non-inflamed retinal vessels have been observed postmortem.
Adaptive optics scanning laser ophthalmoscopy (AO-SLO) facilitates viewing of the in vivo human retina with microscopic resolution and has not been widely applied in MS.
Re: vascular problems in the MS eyes
Novel microscopic foveal pit pathology in multiple sclerosis revealed with adaptive optics ophthalmoscopy
https://iovs.arvojournals.org/article.a ... id=2769442
Conclusions :
Previously unreported microscopic features, not detectable with clinical examination, were observed in the foveal pit of 5 out of 7 MS subjects. Monitoring these structures may be useful as a biomarker for evaluating ocular disease progression in MS.
https://iovs.arvojournals.org/article.a ... id=2769442
Conclusions :
Previously unreported microscopic features, not detectable with clinical examination, were observed in the foveal pit of 5 out of 7 MS subjects. Monitoring these structures may be useful as a biomarker for evaluating ocular disease progression in MS.
Re: vascular problems in the MS eyes
Interesting study! 5 out of 7 subjects with MS had this, that's a high percentage (71.4 percent). Even though a very small sample size. Hopefully they'll follow up with a larger study. Thanks for posting this study.
DX 6-09 RRMS, now SPMS
Re: vascular problems in the MS eyes
Yes. It is something that could yield new information
-
- Similar Topics
- Replies
- Views
- Last post