Does the venous pressure theory of multiple sclerosis pathophysiology deserve a second chance?

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.
Post Reply
User avatar
frodo
Family Elder
Posts: 1749
Joined: Wed Dec 02, 2009 3:00 pm
Contact:

Does the venous pressure theory of multiple sclerosis pathophysiology deserve a second chance?

Post by frodo »

Does the venous pressure theory of multiple sclerosis pathophysiology deserve a second chance?

https://www.sciencedirect.com/science/a ... 4821005290

Summary

The theory that multiple sclerosis is related to venous pressure has been discredited due to previous operator dependent diagnostic criteria and premature attempts at treatment.

- (1) An elevation in venous pressure may only be a component of the compliance changes found in MS.
- (2) The neck veins may only supply a component of the venous pressure elevation found intracranially.

Although a more targeted approach towards neck angioplasty (both towards disease subtype and those with more favorable stenoses) may be beneficial, we would advocate caution. We encourage others to give the venous pressure theory a second chance and to replicate our work.
Post Reply
  • Similar Topics
    Replies
    Views
    Last post

Return to “Chronic Cerebrospinal Venous Insufficiency (CCSVI)”