Have modified Tecfidera startups been successful?

[LaurieLuissa]

I started Tecfidera 4/10/15, with 240 mg twice a day beginning a week later as indicated. Having constant stomach issues now, and am considering stopping Tec permanently. Has anyone had success after MD modified startup schedule, eg taking 120 mg tablets for more than just a week?

[Lucky2be]

Yes! I started 120 mg 1x/day for 2 weeks, then 1x240mg per day for two weeks, then full dose 2x240 mg per day. Only side effect was flushing for the first month and heartburn for a few weeks. No side effects now and I always take it mid meal.

[MI1611]

I started 120 mg 1x/day for 2 weeks, then 2x240mg had some stomach issues: Take them with your breakfeast or diner, after few days it will be fine!
Don't give up!

[Froggie]

I've been on the full dose (2 x 240mg) for almost two years with no problems. I think taking it with food is critical, as I've experienced no stomach upset when I do. In the morning I take it half way through breakfast and my second dose is usually on a full stomach. It's ugly the next morning if I don't do that. Hope this helps.