High dose biotin causes lab test interference

Biotin is an emerging therapy for the treatment of secondary progressive MS.
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NHE
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High dose biotin causes lab test interference

Post by NHE » Thu Sep 26, 2019 2:41 am

If you're taking high-dose biotin then you need to be aware that it will interfere with many medical tests that rely upon biotin/streptavidin immunoassays. This could potentially lead doctors to make incorrect conclusions regarding your health, that in many cases could be critical, e.g. the presence or absence of cancer.

Here is a list presented by Medday of tests which can be distorted by high dose biotin. Note that this list is non-exhaustive and there could be other tests which are not listed, but are still sensitive to biotin interference.

https://medday-lab.com/index.html

Biotin can lead to false low results in sandwich immunoassays.

https://medday-lab.com/sandwishAssays.html

Biotin can lead to false high results in competitive binding immunoassays.

https://medday-lab.com/competitiveAssays.html

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