I've been hypo for a long time. I was 21 when my dr told me to keep an eye on the tsh as mine was high but not yet out of range. When I was around 25, dr finally said I was hypo and I've been on meds ever since. Not too long ago my new endo said he wanted to test me for hashi's and they did so shortly after when I did my normal blood test and of course it came back positive. To me, not a big deal since the way you treat it is to keep doing the exact same thing you did before. Which is take the thyroid meds. So hashi/no hashi, doesn't matter which is why I've never requested the test.
Anyway my tsh has always been unstable on synthroid, I'm hyper, I'm hypo, I'm hyper etc. Several years ago I switched to dessicated and have been relatively steady ever since on the exact same dosage. A couple months ago I started coimbra and about a month ago did my normal thyroid test, and it came back hyper which is abnormal. My thyroid meds haven't increased in ages and if anything I should be trending hypo more as what's left of my thyroid is eroded. Dr asks me to lay off supplements for 3 days, test again. My lab pushes me back a bit so I end up off all supplements for a week or so, only taking my thyroid meds. Test again, comes back hyper, again. Which again, odd. So I've reduced my meds and will be testing again in a few weeks.
So building a theory since I'm not a true coimbra believer yet, but I'm sticking to the program and hoping. Hashi is an autoimmune problem and coimbra according to the dr I went to works for pretty much all AI diseases. I don't have any objective benchmark for the MS symptoms but possibly it IS working and the attack on my thyroid is weakening. If over time my TSH, t3/t4 results continue showing a trend to normalizing I will have literally no other explanation besides the protocol. My thyroid functions was REALLY low when I had it tested a couple years ago (14% of normal if memory serves). I'm not getting any younger. When I was diagnosed I was a gym rat, which I'm not anymore so it's not pure physical fitness. My diet has only changed to accommodate the calcium restrictions. And I've read no-where that there has been a formula change in the meds and now everyone is going hyper. And none of the supplements I take are known for messing with they thyroid direct and with not biotin in the mix (which makes you show suuuuuper hypo anyway) there's nothing that should be skewing the lab results. I can't think of anything else besides the protocol working. I guess we'll see.