Some forms of MS are inherited

[frodo]

Maybe EBV-infection is required to develop MS but a lot of people with EBV do not develop MS. There must be something more.

Some forms of MS could be genetic. A year ago researchers found a mutation linked to the variety "agressive progressive". I posted this, that could be interesting.

http://www.thisisms.com/forum/general-d ... 27913.html

Now the same researchers have found other genetic variety:

Study reveals more evidence that some forms of MS are inherited
http://www.ms-uk.org/study-reveals-more ... ted-180417

Edit: Somebody posted this before in other subforum:
http://www.thisisms.com/forum/news/foru ... erapy-f26/

[SeanReynolds]

EBV? CPn? MAP?

Requires a genetic susceptibility of some ilk, I suppose, in a minority, or else just bad luck of timing during an infection where an infectious particle breaks out of its usual domain and goes systemic or crosses the BBB.

I question whether EBV simply acts as a helper to facilitate a CPn infection.

[SeanReynolds]

David Wheldon suggests EBV and HHV-6 and others are possible 'henchmen' viruses, but facilitating a CPn infection or similar.

http://www.davidwheldon.co.uk/hhv6.html

[SeanReynolds]

Once again, reading that Canadian/Australian research, the findings are completely consonant with acquiring a CPn type infection at some stage in the life span from a family member, and having the genetic immune susceptibility they've recognised which prevents the body fighting the bug. Cpn is transmitted via coughing/sneezing etc and is quite contagious and leads to 10% of community-acquired pneumonia hospital admissions, for instance.

If not CPn, then just possibly the MAP mycobacterium.