MRS (Magnetic Resonance Spectroscopy) can show the chemical composition of the brain. It seems that some chemical markers (the relationship of N-acetyl-aspartate to choline) can diagnose MS before the first lesion appears.
https://www.sciencedirect.com/science/a ... 6018301788
• MRI can identify MS plaques, but its detection of imperceptible disease related abnormalities in normal appearing cervical spinal cord is limited.
• MRS identifies tissue pathologic alterations even before the emergence of plaques in conventional MRI images.
• Reduced tNAA and increased M-Ins are important, sensitive indices for differentiating MS patients from healthy controls.
• MRS data from normal appearing cervical spinal cord enable us to follow MS disease progression and determine disease prognosis.
Imaging biomarkers. Chemical composition by MRS as biomarker
-
- Similar Topics
- Replies
- Views
- Last post
-
- 0 Replies
- 1007 Views
-
Last post by frodo
-
- 0 Replies
- 1392 Views
-
Last post by NHE
-
- 2 Replies
- 1786 Views
-
Last post by jimmylegs
-
- 1 Replies
- 1001 Views
-
Last post by NHE
-
- 0 Replies
- 1608 Views
-
Last post by frodo
-
- 0 Replies
- 1214 Views
-
Last post by frodo
-
- 0 Replies
- 1061 Views
-
Last post by frodo
-
- 0 Replies
- 2505 Views
-
Last post by NHE
-
- 0 Replies
- 1672 Views
-
Last post by frodo