Barts blog: EBV in Brain
Posted: Tue Jul 03, 2018 2:29 am
EBV in Brain
Source: http://multiple-sclerosis-research.blog ... brain.html
The best evidence to date does suggest that EBV is present in both MS and control brains, but is more common in pwMS (90% vs 24%).
Clearly, the presence of EBV-infected B cells in the brain is not sufficient to drive disease activity. Further work needs to be done to understand why some people are perfectly healthy despite having EBV in their brain, whereas others go on to develop MS.
Deeper understanding of how EBV is linked to MS is an essential first step towards developing safe treatments (and vaccines) which target EBV. EBV-targeted treatments are already in early stages of development.
Source: http://multiple-sclerosis-research.blog ... brain.html
The best evidence to date does suggest that EBV is present in both MS and control brains, but is more common in pwMS (90% vs 24%).
Clearly, the presence of EBV-infected B cells in the brain is not sufficient to drive disease activity. Further work needs to be done to understand why some people are perfectly healthy despite having EBV in their brain, whereas others go on to develop MS.
Deeper understanding of how EBV is linked to MS is an essential first step towards developing safe treatments (and vaccines) which target EBV. EBV-targeted treatments are already in early stages of development.