new biomarker, in blood, and maybe able to classify patients
Posted: Thu Feb 21, 2019 6:47 pm
Long non‐coding RNA AFAP1‐AS1 is upregulated in a subset of multiple sclerosis patients
https://onlinelibrary.wiley.com/doi/abs ... cen3.12513
Results
AFAP1‐AS1 was upregulated in male MS patients compared with healthy male controls (P = 0.048). AFAP1 expression was not different between MS patients and controls or between any subgroups of patients and controls. The interaction between disease status and sex was significant in AFAP1‐AS1 expression. There was a significant inverse correlation between expression levels of AFAP1 and AFAP1‐AS1 in healthy individuals (r = −0.472, P = 0.001), but not MS patients (r = −0.251, P = 0.078).
https://onlinelibrary.wiley.com/doi/abs ... cen3.12513
Results
AFAP1‐AS1 was upregulated in male MS patients compared with healthy male controls (P = 0.048). AFAP1 expression was not different between MS patients and controls or between any subgroups of patients and controls. The interaction between disease status and sex was significant in AFAP1‐AS1 expression. There was a significant inverse correlation between expression levels of AFAP1 and AFAP1‐AS1 in healthy individuals (r = −0.472, P = 0.001), but not MS patients (r = −0.251, P = 0.078).