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Dawson fingers in anti-MOG disease

Posted: Sat Jun 01, 2019 9:19 am
by frodo
Anti-MOG disease makes around 10% of diagnosed MS patients and until now was reported only in atypical MS. Dawson fingers was considered one of the specific MS findings and one of the most reliable MRI characteristics of MS.

Now MS fingers have been found in a confirmed anti-MOG patient, making even more clear that MS is just a collection of demyelination cases with unknown origin.

MOG antibody-associated demyelinating disease mimicking typical multiple sclerosis: A case for expanding anti-MOG testing? ... 4819302251


MOG-antibody associated demyelinating disease is a new emerging diagnostic entity. Recently, international recommendations for testing of anti-MOG antibodies were published. Herein, we describe a case of anti-MOG antibody-associated demyelinating disease initially diagnosed as typical MS, and, at presentation, not fulfilling the proposed recommendations. This case highlights the expanding spectrum of anti-MOG antibody-associated demyelinating disease, illustrating the distinct and overlapping features of MS and MOG-antibody associated demyelinating disease, providing evidence that on rare occasions these recommendations may prove too restrictive.