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Reelin depletion for MS

Posted: Sun Aug 30, 2020 10:48 am
by jimmylegs
Reelin depletion protects against autoimmune encephalomyelitis by decreasing vascular adhesion of leukocytes
https://stm.sciencemag.org/content/12/5 ... 5.abstract

"...Our findings suggest Reelin depletion as a therapeutic approach with an inherent good safety margin for the treatment of MS and other diseases where leukocyte extravasation is a major driver of pathogenicity."