https://www.sciencedirect.com/science/a ... njO6uiJwrw
Biomarkers in Multiple sclerosis: what place for oxysterols?
The main markers of multiple sclerosis that have been identified are involved in the pathophysiology of the disease. Mainly derived from cerebrospinal fluid, they are directly related to the mechanisms involved in multiple sclerosis. These biomarkers may be markers of immune activation, markers of blood-brain barrier disruption, markers of demyelination, markers of astrocyte and microglial activation as well as markers of neuronal and axonal damage. Recently, biomarkers of mitochondrial activity as well as lipid markers have been suggested. Among the lipids under consideration are fatty acids and their peroxidation products, phospholipids but also oxysterols which are oxidized cholesterol derivatives [13,14]. Fig. 3 summarizes the different biomarkers detailed in this paragraph.
Biomarkers. Extensive review as of 2021
-
- Similar Topics
- Replies
- Views
- Last post
-
- 0 Replies
- 1721 Views
-
Last post by frodo
-
- 0 Replies
- 1241 Views
-
Last post by frodo
-
- 0 Replies
- 1293 Views
-
Last post by Tif
-
- 0 Replies
- 1577 Views
-
Last post by frodo
-
- 0 Replies
- 1024 Views
-
Last post by frodo
-
- 0 Replies
- 1151 Views
-
Last post by frodo
-
- 0 Replies
- 2477 Views
-
Last post by NHE
-
- 0 Replies
- 1631 Views
-
Last post by frodo
-
- 0 Replies
- 1369 Views
-
Last post by frodo