Injection Site Immediate Bump Reactions

A board to discuss the Multiple Sclerosis modifying drug Rebif
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Injection Site Immediate Bump Reactions

Post by FourDs » Fri Aug 25, 2006 6:56 pm

Hey everyone,

I am posting something that is actually happening to my fiancee. She was diagnosed with MS in October 2005, and has been taking a form of Interferon since then. First, she took Avonex which I injected for her. That did not stop exacerbations, so she switched to Rebif.

After taking Rebif for around 5 months, all of a sudden where she injects she is getting a site reaction that is immediate. It looks almost like a mosquito bite, hard to describe. If she massages the area it will go down after about 5 minutes.

This is a strange development and we are wondering if there is something wrong? Is this normal? Is there anyway to fix it?

Thanks for any help and support!


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Post by carolsue » Sat Aug 26, 2006 2:07 pm

This has never happened to me, so I can't really help you. Call your nurse/doctor or Rebif's hotline to ask. My guess (which is hardly even educated) is that as long as the bump goes away, it's not a big worry.

Interferon's a harsh thing, and you don't want to get it on your skin (and yet we inject it under our skin...). Try to make sure there's not a drop on the tip of the needle. Pulling up on the plunger ever so slightly before removing the cap sure helps with this.


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Post by oreo » Sat Aug 26, 2006 6:06 pm

Does she pre-warm the injection.

5 minutes in the armpit will bring the serum up to her body temp - less of a shock to the system. Also, inject slowly. With that very tiny needle, a speedy injection turns the syringe into a high pressure hydraulic cutting device.
Carpe Diem

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