Siponimod study in secondary-progressive multiple sclerosis

Mayzent is an oral treatment for relapse remitting MS and active secondary progressive MS.
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MSUK
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Siponimod study in secondary-progressive multiple sclerosis

Post by MSUK » Mon Jan 27, 2014 5:30 am

A new clinical trial is underway for individuals who have secondary progressive multiple sclerosis (SPMS). Patients with SPMS generally have had relapsing-remitting MS, but now are having attacks that are less frequent and less well defined. Patients don’t generally recuperate from these attacks and disabilities begin set in. It is reported that 80% of patients with relapsing-remitting MS eventually develop secondary progressive Multiple Sclerosis, and this process tends to begin 15 or so years after being diagnosed with MS...... Read More - http://www.ms-uk.org/emergingtherapies
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Re: Siponimod study in secondary-progressive multiple sclero

Post by HarryZ » Mon Jan 27, 2014 6:34 am

MSUK wrote:A new clinical trial is underway for individuals who have secondary progressive multiple sclerosis (SPMS). Patients with SPMS generally have had relapsing-remitting MS, but now are having attacks that are less frequent and less well defined. Patients don’t generally recuperate from these attacks and disabilities begin set in. It is reported that 80% of patients with relapsing-remitting MS eventually develop secondary progressive Multiple Sclerosis, and this process tends to begin 15 or so years after being diagnosed with MS...... Read More - http://www.ms-uk.org/emergingtherapies
The article mentions that 80% of R/R MS patients go on to develop SPMS....and this happens despite all the immune system altering drugs that have been developed in the past 25 years. So now they are going to try another monoclonol antibody drug in an attempt to stop the disease in SPMS patients!! Why am I not confident this will lead to any kind of major benefit?!

Harry

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