Actual details on reduced Lymphocytes count?

[CureOrBust]

I tried doing a search to find the actual numeric effects on cell counts of circulating Lymphocytes before and after being on Gilenya. I didn't find it. The best I found was an approximation for mice in an experiment, who I would assume would of been on much more severe doses.

I would love to see the data from the Phase II and Phase III trials; which used different dosages? Is this data available anywhere?

Even better would be a graph plotting treatment response (eg EDSS) to Lymphocyte reductions, if there is any pattern to the response.

[Shayk]

Hi Cure

I don't have a clue if the info you want is in these documents but this is a link to info
on the FDA website about Gilenya.

Take care

Sharon

[CureOrBust]

I did a quick skim read, and it appears to be a wealth of info. Thanks.

[lmacalus]

Have you tried calling Novartis & asking them? Could it be contained in the PI?