Elevated blood pressure and pulse on Tecfidera

Discuss Tecfidera (BG-12, dimethyl fumarate) as an oral treatment for multiple sclerosis.
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Elevated blood pressure and pulse on Tecfidera

Post by Pookie » Wed Jul 17, 2013 3:37 pm

My husband started taking Tecfidera about 3weeks ago. He did great on the 120 mg 2x per day but midway into the 2nd week on the 240 mg 2x per day, he got very weak, had a fever, heart rate and pulse were elevated. Ended up having the EMTs come and take him to the hospital. Took him off the Tecfidera and he was well enough to come home in 3 days. His neurology said to start him on one 240 mg once a day. I gave him that ths morning and he just doesn't feel good. Blood pressure is up ad so s puse. Anyone ese have this problem?

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Re: Elevated blood pressure and pulse on Tecfidera

Post by azmsgal » Wed Jul 17, 2013 5:02 pm


Had to stop this drug 6 days in... I couldn't take the side effects. Severe cramping and abdominal pain, sweating, constipation, nausea and vomiting, and explosive diarrhea. I never made it to the 240mg dose, but for those that have, I hear they are happy. I wish so very much I could tolerate this drug, but after my experience...Rebif is looking like a heavenly choice (Never ever thought I would say that) Good luck and I hope your husband feels better.

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Re: Elevated blood pressure and pulse on Tecfidera

Post by trapper » Wed Sep 25, 2013 11:47 am

Yes. After 2 and 1/2 days, I had all the classic symptoms along with elevated pulse. Also I had a seizure. My doctor does not want to entertain the idea that Tecfidera caused the seizure but I have read that other people have had seizures. Good luck to your husband.

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