A-10 year case study of a doctor on high dose vitamin D

[PointsNorth]

http://www.ncbi.nlm.nih.gov/pmc/article ... -13461.pdf

From Grassroots health.

Her website: Dr. Barb Van A, DDS PhD website. She's had MS since the mid-70s and cured herself using a hi dose of vitamin D.

http://www.vitamindandms.org/

All this Anecdotal Evidence is frustrating me!

[Scott1]

Hi,

I looked on that page and somehow missed the link. I did find this instead - http://www.ncbi.nlm.nih.gov/pubmed/26286698

"Patients with MS had a lower increase in 25(OH)D levels with supplementation, even after accounting for putative confounders."

Isn't why does that happen the central question ?

Regards,

[PointsNorth]

Scott,

I tried both of the links again and they work as advertised. A few years ago I did genetic testing and I was found to be homozygous for the VDR Taq mutation. Since then I found another person with MS who also has this mutation. I suspect that most if not all people with MS have this mutation requiring them to take high doses of vitamin D to reverse the course of MS.

PN

[MStranslate]

Scott,

I tried both of the links again and they work as advertised. A few years ago I did genetic testing and I was found to be homozygous for the VDR Taq mutation. Since then I found another person with MS who also has this mutation. I suspect that most if not all people with MS have this mutation requiring them to take high doses of vitamin D to reverse the course of MS.

PN

The entire Vitamin D story and MS is obviously very interesting and there are lots of studies coming out at the moment. In terms of the VDR Taq mutation, it will be interesting to see how this looks across different populations. I know in some locations they have found that the mutation wasn't found in large numbers in people with MS, but this isn't necessarily true everywhere.

The other question posed was why don't people with MS respond to Vitamin D supplementation? Again, this is a great question, but not a simple one to answer. Trust me, as an MS researcher, I know exactly how frustrating it is that there are never any simple answers to these questions! Some studies have certainly shown that high-dose Vitamin D supplementation does increase the levels in people with MS. One in particular from the start of the year not only showed that, but also showed that it had an impact on certain cells of the immune system that are implicated as causing damage in MS. You can read the summary of this study on our website:

http://www.mstranslate.com.au/vitamin-d ... treatment/

Happy to answer any other questions on this and keep contributing to this discussion! I'm reading a study at the moment about a new publication from a group in Sydney, Australia that indicates another potential role for Vitamin D. Watch this space!

[CureOrBust]

Just for clarity and differentiation from Coimbra, the treatment spoke of is 10,400IU

[PointsNorth]

Scott,

I tried both of the links again and they work as advertised. A few years ago I did genetic testing and I was found to be homozygous for the VDR Taq mutation. Since then I found another person with MS who also has this mutation. I suspect that most if not all people with MS have this mutation requiring them to take high doses of vitamin D to reverse the course of MS.

PN

The entire Vitamin D story and MS is obviously very interesting and there are lots of studies coming out at the moment. In terms of the VDR Taq mutation, it will be interesting to see how this looks across different populations. I know in some locations they have found that the mutation wasn't found in large numbers in people with MS, but this isn't necessarily true everywhere.

The other question posed was why don't people with MS respond to Vitamin D supplementation? Again, this is a great question, but not a simple one to answer. Trust me, as an MS researcher, I know exactly how frustrating it is that there are never any simple answers to these questions! Some studies have certainly shown that high-dose Vitamin D supplementation does increase the levels in people with MS. One in particular from the start of the year not only showed that, but also showed that it had an impact on certain cells of the immune system that are implicated as causing damage in MS. You can read the summary of this study on our website:

http://www.mstranslate.com.au/vitamin-d ... treatment/

Happy to answer any other questions on this and keep contributing to this discussion! I'm reading a study at the moment about a new publication from a group in Sydney, Australia that indicates another potential role for Vitamin D. Watch this space!

@ MSTranslate - Check out the forum: Coimbra High-Dose Vitamin D Protocol - This Is MS Multiple Sclerosis Community: Knowledge & Support

http://www.thisisms.com/forum/coimbra-h ... tocol-f57/

[MStranslate]

Scott,

I tried both of the links again and they work as advertised. A few years ago I did genetic testing and I was found to be homozygous for the VDR Taq mutation. Since then I found another person with MS who also has this mutation. I suspect that most if not all people with MS have this mutation requiring them to take high doses of vitamin D to reverse the course of MS.

PN

The entire Vitamin D story and MS is obviously very interesting and there are lots of studies coming out at the moment. In terms of the VDR Taq mutation, it will be interesting to see how this looks across different populations. I know in some locations they have found that the mutation wasn't found in large numbers in people with MS, but this isn't necessarily true everywhere.

The other question posed was why don't people with MS respond to Vitamin D supplementation? Again, this is a great question, but not a simple one to answer. Trust me, as an MS researcher, I know exactly how frustrating it is that there are never any simple answers to these questions! Some studies have certainly shown that high-dose Vitamin D supplementation does increase the levels in people with MS. One in particular from the start of the year not only showed that, but also showed that it had an impact on certain cells of the immune system that are implicated as causing damage in MS. You can read the summary of this study on our website:

http://www.mstranslate.com.au/vitamin-d ... treatment/

Happy to answer any other questions on this and keep contributing to this discussion! I'm reading a study at the moment about a new publication from a group in Sydney, Australia that indicates another potential role for Vitamin D. Watch this space!

@ MSTranslate - Check out the forum: Coimbra High-Dose Vitamin D Protocol - This Is MS Multiple Sclerosis Community: Knowledge & Support

http://www.thisisms.com/forum/coimbra-h ... tocol-f57/

@PointsNorth - thanks for the link, I will certainly give it a look! I hope I wasn't out of place in entering into the discussion? I just thought that it helped answer a couple of questions that had been raised.

[PointsNorth]

Always welcome MSTrans!