Promising results in human trial

bromley · Post by **bromley** » Fri Jan 30, 2009 1:39 am

http://news.bbc.co.uk/1/hi/health/7858559.stm

Jamie · Post by **Jamie** » Tue Feb 03, 2009 3:57 pm

looks extremely interesting.

gone to national trial and also use chemo first to 'reboot'.

i'd be trying to get Mel on this if she hadn't had HiCy.

CureOrBust · Post by **CureOrBust** » Tue Feb 03, 2009 10:49 pm

Study leader Professor Richard Burt said this was the first MS study of any treatment to show reversal of damage.

Wouldn't Campath or HyCy have been first?

cheerleader · Post by **cheerleader** » Thu Feb 05, 2009 1:39 pm

Northwestern's Feinberg School is recruiting for Phase II NOW....

Clinical Trials link:
http://clinicaltrials.gov/ct2/show/NCT00273364

CHICAGO --- Researchers from Northwestern University's Feinberg School of Medicine appear to have reversed the neurological dysfunction of early-stage multiple sclerosis patients by transplanting their own immune stem cells into their bodies and thereby "resetting" their immune systems.

"This is the first time we have turned the tide on this disease," said principal investigator Richard Burt, M.D. chief of immunotherapy for autoimmune diseases at the Feinberg School. The clinical trial was performed at Northwestern Memorial Hospital where Burt holds the same title.

The patients in the small phase I/II trial continued to improve for up to 24 months after the stem cell transplant and then stabilized. They experienced improvements in areas in which they had been affected by multiple sclerosis including walking, ataxia, limb strength, vision and incontinence. The study will be published online January 30 and in the March issue of The Lancet Neurology.