Teriflunomide
- domheldercamara
- Newbie
- Posts: 2
- Joined: Thu Dec 17, 2009 3:00 pm
- Location: Ottawa, Canada
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New to the Site- Thinking of Teriflunomide Clinical Study
My MD asked me if I was interested in participating in the phase III study as I am pretty well petrified of needles...
I am reading the consent form and it says something to the effect that the drug has shown (in test tube studies) alterations to DNA- and can potentially cause cancer..but there is no proof yet in humans.
It makes me equally nervous.
Can anyone speak to the effects the drug has had on them. I understand that hair loss is one of them- its the cancer that really scares me, any words of advice?
Thanks
I am reading the consent form and it says something to the effect that the drug has shown (in test tube studies) alterations to DNA- and can potentially cause cancer..but there is no proof yet in humans.
It makes me equally nervous.
Can anyone speak to the effects the drug has had on them. I understand that hair loss is one of them- its the cancer that really scares me, any words of advice?
Thanks
- domheldercamara
- Newbie
- Posts: 2
- Joined: Thu Dec 17, 2009 3:00 pm
- Location: Ottawa, Canada
- Contact:
Teriflunomide
Hey DM,
Thanks for making me less nervous about teriflunomide. I will be at the General with Dr. Christie for the trials.
I am glad to know that there is someone on the forum not only in proximity, but on the same trial.
Thanks again, I think now I will have less trepidation to try this drug out.
Thanks for making me less nervous about teriflunomide. I will be at the General with Dr. Christie for the trials.
I am glad to know that there is someone on the forum not only in proximity, but on the same trial.
Thanks again, I think now I will have less trepidation to try this drug out.
Bad news
So, it seems I have 3 new lesions, so am washing out of the drug next week. Oh well, was worth a try. 9 months, no symptoms, perhaps the Placebo, will never know.
Looking into Avonex now.
tbh, its good timing, i was about to go travelling for a year, and the drug company was insist that i travel back to London every 6 weeks for blood tests, which would have been expensive.
Still don't have MS by definition, but as the Doctor says "the ongoing activity is highly suggestive".
Good news in the paper yesterday
Hope for MS pill after cladribine and fingolimod trials
http://news.bbc.co.uk/1/hi/health/8470138.stm
Looking into Avonex now.
tbh, its good timing, i was about to go travelling for a year, and the drug company was insist that i travel back to London every 6 weeks for blood tests, which would have been expensive.
Still don't have MS by definition, but as the Doctor says "the ongoing activity is highly suggestive".
Good news in the paper yesterday
Hope for MS pill after cladribine and fingolimod trials
http://news.bbc.co.uk/1/hi/health/8470138.stm
- sneakypuss_01
- Getting to Know You...
- Posts: 10
- Joined: Wed Oct 14, 2009 2:00 pm
- Location: Sydney Australia
- Contact:
Hi All
Just wanted to let you know that I am participating in the phase III trial here in Australia.
I get put into 'randomization' ion May 4th. So far, I am only the second person at my MS Clinic to go into the trial.
Hope everyone is well.
Sneaky P
Just wanted to let you know that I am participating in the phase III trial here in Australia.
I get put into 'randomization' ion May 4th. So far, I am only the second person at my MS Clinic to go into the trial.
Hope everyone is well.
Sneaky P
There's not brain lesions...their bright ideas.
DX July 1st 2009 RRMS
DX July 1st 2009 RRMS
- sneakypuss_01
- Getting to Know You...
- Posts: 10
- Joined: Wed Oct 14, 2009 2:00 pm
- Location: Sydney Australia
- Contact:
For those interested in the trial, here's the offical website:
http://tower3.msstudies.com/index.php
http://tower3.msstudies.com/index.php
There's not brain lesions...their bright ideas.
DX July 1st 2009 RRMS
DX July 1st 2009 RRMS
- sneakypuss_01
- Getting to Know You...
- Posts: 10
- Joined: Wed Oct 14, 2009 2:00 pm
- Location: Sydney Australia
- Contact:
Re: Teriflunomide
It has been a while since my last post. I am still on the extended study, still not knowing what I was taking during the trial, several years ago. As of now, I am scheduled to be off the drug in June 2013, unless it gets extended once again. My ultrasounds have stopped although the MRIs continue.
I have had no side FX whatsoever, and the toughest thing is remembering to take the pills. I must have downed hundreds of these lil guys already, and I feel no different. Maybe that a good thing since I have no ill FX from the MS whatsoever.
My hair is still thinning and at this rate, I will be bald in 3 years. Still have a chunk of good hair as long as I dont comb it but when it is wet, like out of the shower, my scalp is visible. Wait til it dries and no one knows the difference.
My nurse says that they are having good success with this drug, maybe they are, I do not know, but it has not bothered me whatsoever. Doubt it the cure but maybe in keeps the MS in check. 7mg or 14, couldn't tell you. Not til they open the books when everything is said and done. Sure happy I am not injecting myself.
So, another year and I guess that is it. After that, not sure.
Anyhow, just thought I would chime in after not being here for so long
I have had no side FX whatsoever, and the toughest thing is remembering to take the pills. I must have downed hundreds of these lil guys already, and I feel no different. Maybe that a good thing since I have no ill FX from the MS whatsoever.
My hair is still thinning and at this rate, I will be bald in 3 years. Still have a chunk of good hair as long as I dont comb it but when it is wet, like out of the shower, my scalp is visible. Wait til it dries and no one knows the difference.
My nurse says that they are having good success with this drug, maybe they are, I do not know, but it has not bothered me whatsoever. Doubt it the cure but maybe in keeps the MS in check. 7mg or 14, couldn't tell you. Not til they open the books when everything is said and done. Sure happy I am not injecting myself.
So, another year and I guess that is it. After that, not sure.
Anyhow, just thought I would chime in after not being here for so long