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I agree that saturated fat is required in a healthy adults diet, but I have MS, and in my case i believe saturated fats are not beneficial. The original Swank study is what i put the most faith in due to its direct focus on disability progression and the results demonstrated. It was critized for a lack of study controls but that does not change the fact that the majority of participants remained ambulant into there 70s. You can fake statistics and tweak percentages but you cannot fake pwMS walking around and remaining active late in life.

jimmylegs wrote:a couple would be good, maybe there's a review article or something?

Take your pick, you can just dump the title into google to get the content. I had the links for the last dozen or so in my bookmarks. I found the saturated fat damaging the endothelial particularly interesting as many consider MS to be a BBB issue more than auto-immune.

original Swank study
https://jama.jamanetwork.com/article.as ... ultClick=1

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Sat fat effect on the endothelium (BBB)
http://www.ncbi.nlm.nih.gov/pubmed/3606733

Endothelial description
http://www.lab.anhb.uwa.edu.au/mb140/mo ... dothel.htm

Sat fat damaging endothelial cells particularly palmitic and stearic
http://www.ncbi.nlm.nih.gov/pubmed/1604444

Low fat diets reduce thrombin
http://www.researchgate.net/publication ... w_fat_diet

Thrombin and subendothelium
http://www.ncbi.nlm.nih.gov/pubmed/11307830

Consumption of saturated fat impairs the anti-inflammatory properties of high-density lipoproteins and endothelial function.
http://www.ncbi.nlm.nih.gov/pubmed/16904539

Consumption of an SAFA-rich meal is harmful for the endothelium, while a MUFA-rich meal does not impair endothelial function
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584179/

saturated NEFAs (palmitate and stearate) are proapoptotic, and unsaturated NEFAs (palmitoleate, oleate, and linoleate) are antilipoapoptotic
http://diabetes.diabetesjournals.org/co ... /3121.full

BBB issue in MS
http://www.ncbi.nlm.nih.gov/pubmed/14664465

BBB functional roles
http://www.ncbi.nlm.nih.gov/pubmed/17453713

EBV and Fatty Acids
http://www.ncbi.nlm.nih.gov/pubmed/15047835

thx

saturated fat damaging the endothelial particularly interesting as many consider MS to be a BBB issue more than auto-immune

perfect, i can provide complementary research for insight on that aspect. (later - physio shortly)