Posted: Tue Nov 09, 2010 1:13 pm
For some of us there is suspicion that injury was a factor in the timing of MS onslaught.
For others the similarity of our injury symptoms and the MS disease (dx) is apparently difficult to separate.
The physical likely hood of injury, stretching, damage causing inflammation, nerve damage, CSF containment system damage, damage to vascularture, damage to tissue and muscle are factors that cannot be ruled out of the study of MS incident.
The timing, severity, and ability to hasten the onset of MS from injury is a yet to be studied causical factor in MS progression.
Until the mechanisms of MS are known the involvement of injury has more logical and statistical likely hood than the other theories such as auto-immune system.
The degree that injury speeds the MS process is yet to be qualified and to do so is going to be a challenge. Dismissing it at this point of CCSVI awareness would be foolish.
The factors that manipulate MS are likely to be Vascular. The actual cause and mechanism of MS is likely to be influenced by many factors which are now being seen to modify the disease. The changes made to the symptoms of MS from angio treatment of veins indicates that 'we' are searching in the 'right' areas. Whether the changes to the vascular system achieved by angio are the sole issue in MS seems unlikely from the outcomes so far.
With broader understanding of the whole Arterial and Venous systems of the brain and upper skeleton and their interaction with the CSF system we will have a new understanding of many diseases, and especially degenerative diseases of the CNS.
Too rule out injury at this point is missing too much detail in the mechanism of MS, there is likely to be insights from the way injury accelerates the progression of degenerative diseases, we need to learn from this.
The belief that MS has a causical structure development related to time has been unproven. By this I mean that saying MS does not speed up from example injury is not based in fact. Examples where mental stress brings on exacerbations is a case in point. We cannot say that an event will NOT accelerate the disease. Many examples of general ill health have caused an increase in progression and speed of progression. On that basis we have to look seriously at physical injury and its effect to understand more about the disease mechanism. Physical injury activates an inflammatory clean up action which we see in RRMS as well. The likely effect on a person with PPMS is yet to be verified, although my personal experience is that disease progression increases during and after injury.
There is a poorly understood interplay within the Blood flow in and out of the upper body, its effects on CSF are a case in point. The balancing of this system also needs to be understood to better understand the dynamics that effect degenerative diseases, especially MS.(Many Scars)
Thank you Dr. Flanagan for your commitment to this learning.
Regards Nigel
For others the similarity of our injury symptoms and the MS disease (dx) is apparently difficult to separate.
The physical likely hood of injury, stretching, damage causing inflammation, nerve damage, CSF containment system damage, damage to vascularture, damage to tissue and muscle are factors that cannot be ruled out of the study of MS incident.
The timing, severity, and ability to hasten the onset of MS from injury is a yet to be studied causical factor in MS progression.
Until the mechanisms of MS are known the involvement of injury has more logical and statistical likely hood than the other theories such as auto-immune system.
The degree that injury speeds the MS process is yet to be qualified and to do so is going to be a challenge. Dismissing it at this point of CCSVI awareness would be foolish.
The factors that manipulate MS are likely to be Vascular. The actual cause and mechanism of MS is likely to be influenced by many factors which are now being seen to modify the disease. The changes made to the symptoms of MS from angio treatment of veins indicates that 'we' are searching in the 'right' areas. Whether the changes to the vascular system achieved by angio are the sole issue in MS seems unlikely from the outcomes so far.
With broader understanding of the whole Arterial and Venous systems of the brain and upper skeleton and their interaction with the CSF system we will have a new understanding of many diseases, and especially degenerative diseases of the CNS.
Too rule out injury at this point is missing too much detail in the mechanism of MS, there is likely to be insights from the way injury accelerates the progression of degenerative diseases, we need to learn from this.
The belief that MS has a causical structure development related to time has been unproven. By this I mean that saying MS does not speed up from example injury is not based in fact. Examples where mental stress brings on exacerbations is a case in point. We cannot say that an event will NOT accelerate the disease. Many examples of general ill health have caused an increase in progression and speed of progression. On that basis we have to look seriously at physical injury and its effect to understand more about the disease mechanism. Physical injury activates an inflammatory clean up action which we see in RRMS as well. The likely effect on a person with PPMS is yet to be verified, although my personal experience is that disease progression increases during and after injury.
There is a poorly understood interplay within the Blood flow in and out of the upper body, its effects on CSF are a case in point. The balancing of this system also needs to be understood to better understand the dynamics that effect degenerative diseases, especially MS.(Many Scars)
Thank you Dr. Flanagan for your commitment to this learning.
Regards Nigel