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2024 Nov 13 Association Between Particulate Matter Pollutants and Ophthalmology Visits for Ocular Surface Irritation and Allergy https://pubmed.ncbi.nlm.nih.gov/39555215/
Conclusion: This study found that ambient PM increased the rate of ophthalmology visits due to ocular surface irritation and allergies. Most importantly, this association increased in magnitude with higher ambient PM concentrations. Additional studies are required to fully understand the effects of climate change-related stressors on ocular health.
Re: PM10
Posted: Tue Nov 19, 2024 9:41 am
by Petr75
2024 Nov 1 How air pollution influences the difference between overweight and obesity: a comprehensive analysis of direct and indirect correlations https://pubmed.ncbi.nlm.nih.gov/39555028/
Conclusion: Air pollution was generally associated with an increased risk of overweight and obesity, with PM2.5 and PM10 having a positive influence, while SO2 and CO had a negative impact. The effect of air pollution was more pronounced among men, older individuals, and rural populations compared to women, younger individuals, and urban populations. Additionally, social behavior factors, such as physical activity, sedentary behavior, sleep, smoking, alcohol consumption, and mental health, predominantly mediated the relationship between air pollution and obesity.
2024 Oct 30 Causal associations of ambient particulate matter 10 and Alzheimer's disease: result from a two-sample multivariable Mendelian randomization study https://pubmed.ncbi.nlm.nih.gov/39649256/
Conclusions: Increased PM10 levels were found to be significantly related to an increased risk of AD. This study provided evidence of genetic prediction of a causal relationship between PM10 and the risk of AD, suggesting that air pollution control may have significant implications for the prevention of AD.
Re: PM10
Posted: Mon Dec 16, 2024 8:31 am
by Petr75
2024 Dec 11
Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, University of Chinese Academy of Sciences, China Association between long-term ambient air pollution exposure and the incidence of breast cancer: A meta-analysis based on updated evidence https://pubmed.ncbi.nlm.nih.gov/39667318/
Conclusion: This study is the first to document a significant association between long-term exposure to ambient PM2.5 and breast cancer incidence through meta-analysis. Air pollution has a pronounced impact on postmenopausal breast cancer, and the strength of the association between specific air pollutants and breast cancer incidence varies across regions. These findings suggest that long-term exposure to NO2 and PM2.5 may increase the incidence of breast cancer.
2024 Dec 5 The Association Between Air Pollution Exposure and White Blood Cell Counts: A Nationwide Cross-Sectional Survey in South Korea https://pubmed.ncbi.nlm.nih.gov/39685860/
2021 Nov 16 White blood cell count profiles in multiple sclerosis during attacks before the initiation of acute and chronic treatments posting.php?mode=reply&t=30257#preview
Re: PM10
Posted: Wed Dec 18, 2024 1:15 pm
by Petr75
Petr75 wrote: ↑Wed Dec 11, 2024 3:25 am
2024 Oct 30 Causal associations of ambient particulate matter 10 and Alzheimer's disease: result from a two-sample multivariable Mendelian randomization study https://pubmed.ncbi.nlm.nih.gov/39649256/
Conclusions: Increased PM10 levels were found to be significantly related to an increased risk of AD. This study provided evidence of genetic prediction of a causal relationship between PM10 and the risk of AD, suggesting that air pollution control may have significant implications for the prevention of AD.
2024 Nov 29 Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases https://pubmed.ncbi.nlm.nih.gov/39682726/
..We observed that differentially expressed genes (DEGs) in HSV-1-infected sc-islets were enriched for genes associated with several autoimmune diseases, most significantly, T1D, but also rheumatoid arthritis, psoriasis, Crohn's disease, and multiple sclerosis
..Additive interactions were also observed for genetic risk and PMcoarse (RERI: 0.04, 95% CI: 0.00-0.07) and PM10 (RERI: 0.04, 95% CI: 0.02-0.06) on SLE risk. In conclusion, our findings emphasize the significance of evaluating the impacts of long-term exposure to ambient air pollutants in preventing SLE, and highlight the necessity to identify individuals who smoke and have a high genetic risk to minimize the harmful effects of air pollution on the development of SLE.
Abstract Autism spectrum disorder (ASD) is a neurodevelopmental disorder caused by the interaction of genetic and complex environmental factors. The prevalence of autism has dramatically increased in countries and regions undergoing rapid industrialization and urbanization. Recent studies have shown that particulate matter (PM) in air pollution affects the development of neurons and disrupts the function of the nervous system, leading to behavioral and cognitive problems and increasing the risk of ASD. However, research on the mechanism of environmental factors and ASD is still in its infancy.
Re: PM10
Posted: Wed Dec 25, 2024 12:28 pm
by Petr75
2024 Dec 20 Air pollution is linked to cognitive decline independent of hypersensitive C-reactive protein: insights from middle-aged and older Chinese https://pubmed.ncbi.nlm.nih.gov/39707297/
Results: A total of 6434 participants were included in the study. Lower exposure to PM2.5, PM1, PM10 and NO2 were associated with mitigated cognitive decline.
Conclusion: Ambient air pollution exposure was linked to cognitive decline independent of hs-CRP level.
In conclusion, gene expression analysis performed in two independent cohorts suggests that PM2.5 exposure in children may be involved in interferon and microbial infection responses.
Re: PM10
Posted: Sun Dec 29, 2024 11:21 am
by Petr75
2024 Dec 17
National Institute for Health Research (NIHR) School for Public Health Research (NIHR SPHR), UK; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK Longitudinal associations between air pollution and incident dementia as mediated by MRI-measured brain volumes in the UK Biobank https://pubmed.ncbi.nlm.nih.gov/39732110/
Abstract
Background: Although there is increasing evidence that environmental exposures are associated with the risk of neurodegenerative conditions, there is still limited mechanistic evidence evaluating potential mediators in human populations.
Conclusions: This study adds to existing evidence of associations between environmental exposures and dementia outcomes. Our findings provide novel evidence that differences in brain volume may mediate these relationships. Future research is required to prove this mechanism and establish the other mechanisms through which exposure to air pollution might increase dementia risk.