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2025 Apr 9 Associations between air pollutants and emergency ambulance dispatches for all-cause and nervous system disease in China Qingdao: a time-stratified case-crossover study https://pubmed.ncbi.nlm.nih.gov/40202545/
..Additionally, O3 (lag0 days), CO (lag0 days), PM10 (lag0 days), and NO2 (lag0 days) exhibited positive correlations with an elevated risk of NS-EADs. To be specific, with every 10 μg/m3 increase in the concentrations of O3, CO, PM10, and NO2 at lag 0, there was a corresponding increase in NS-EADs risk of 0.67% (95% confidence interval,..
Abstract
Although the phenomenon that omega-3 polyunsaturated fatty acids (n-3 PUFAs) shows to have a beneficial effect in patients suffering from multiple sclerosis (MS) and other autoimmune diseases has been empirically well-documented, the molecular mechanisms that underline the anti-inflammatory effects of n-3 PUFAs are yet to be understood. In experimental autoimmune encephalomyelitis (EAE), a model for MS..
2024 Jun 14 Migraine Risk in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder: A Nationwide Cohort Study in South Korea https://pubmed.ncbi.nlm.nih.gov/38880093/
Conclusion: The study results revealed an increased risk of migraines in patients with MS but not in patients with NMSOD compared with matched controls.
Conclusion: Migraine was associated with an increased odds of MS only when co-occurrence was considered. These findings imply that migraines are part of the constellation of MS onset symptoms rather than a risk factor for or prodromal symptom of MS.
2025 Apr 17 Association between weather conditions and migraine: a systematic review and meta-analysis https://pubmed.ncbi.nlm.nih.gov/40246758/
--Moreover, increased levels of air pollutants, including PM10 (OR = 1.07, 95% CI = 1.03-1.11), PM2.5 (OR = 1.04, 95% CI = 1.01-1.06), NO2 (OR = 1.08, 95% CI = 1.03-1.14), CO (OR = 1.08, 95% CI = 1.01-1.16), and O3 (OR = 1.12, 95% CI = 1.03-1.21), were significantly associated with an increased risk of migraine clinical visits, whereas SO2 (OR = 1.02, 95% CI = 1.00-1.04) was no
2025 Apr 18
Association of ambient ozone with time to pregnancy and the modifying effect of ambient temperature: a population-based cohort study https://pubmed.ncbi.nlm.nih.gov/40254269/
Re: Tropospheric ozone
Posted: Fri Apr 25, 2025 6:31 am
by Petr75
O3
2025 Apr 23 Interactions among Cupressaceae pollen, air pollutants and meteorology in the urban and suburban areas of Beijing, China https://pubmed.ncbi.nlm.nih.gov/40269145/
.. Concentration weighted trajectory (CWT) results indicated that allergenic pollen and O3 may have some common potential source areas. This research will help us to get a better understanding of the linkage between allergenic pollen and air pollutants, and their dynamics under varying meteorological conditions, and provide effective support on addressing respiratory allergies on the risk of co-exposure for allergenic pollen and air pollutants in the urban and suburban areas of Beijing city
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There are many things that experts do not understand about multiple sclerosis (MS). For example, they do not know what causes MS. However, research shows there may be a link between MS and allergies.1,2
This link is not yet proven, but researchers are studying the possible connection. They are also trying to learn what this connection could mean for MS treatments.1,2
Is there a link between MS and allergies?.....
2025 Apr 23
Division of Cancer Prevention, National Cancer Control Institute, National Cancer Center, Goyang, Korea Long-term ambient ozone exposure and lung cancer mortality: a nested case-control study in Korea https://pubmed.ncbi.nlm.nih.gov/40280269/
..Furthermore, regional differences were observed, with a significantly higher risk in rural areas. Findings of this study suggest that long-term exposure to O3, especially in combination with PM2.5 exposure, is associated with an excess risk of lung cancer mortality, underscoring the importance of addressing the O3 and PM2.5 interaction in lung cancer prevention.
• MR analysis showed that MS is a causal risk factor of lung cancer.
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October 2020
sciencedirect.com Prevalence of multiple sclerosis in rural and urban districts in Telemark county, Norway https://www.sciencedirect.com/science/a ... 4820304272
• The prevalence are even higher in rural areas of Telemark, in 2019 the prevalence rates were 250.4/105 in urban and 316.2 /105 in rural areas.
Low oxygen availability (hypoxia) is a prominent but poorly understood feature in multiple sclerosis (MS). Whether hypoxia causes or drives MS pathology and symptoms or whether it is a consequence of other pathological events, such as inflammation and vascular dysfunction, is unknown. Here, we summarize the available literature on the interplay between hypoxia and both pathological and symptomatic features of MS. Severe environmental hypoxia (i.e., altitude) may trigger or facilitate MS-related events, possibly by exacerbating tissue hypoxia in the central nervous system...
Re: Tropospheric ozone
Posted: Sun May 18, 2025 8:53 am
by Petr75
Re: Tropospheric ozone
Posted: Sun May 18, 2025 8:58 am
by Petr75
O3
2025 May 1 Personal exposure to PM2.5 and O3 induced heterogeneous inflammatory responses and modifying effects of smoking: A prospective panel study in COPD patients https://pubmed.ncbi.nlm.nih.gov/40378747/
..This study emphasizes the need for personalized prevention strategies to protect COPD patients from the detrimental impacts of air pollution and smoking.
2008 May-Jun Increased prevalence of multiple sclerosis among COPD patients and their first-degree relatives: a population-based study https://pubmed.ncbi.nlm.nih.gov/18351419/
..These diseases may share inflammatory pathways, including predisposing variants of genes.
2017 Nov 21
Department of Chemistry, SUNY College of Environmental Science and Forestry, Syracuse Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients https://pubmed.ncbi.nlm.nih.gov/29157250/
Abstract
Background: Air pollution is a major risk factor for cardiovascular disease, of which ozone is a major contributor. Several studies have found associations between ozone and cardiovascular morbidity, but the results have been inconclusive. We investigated associations between ozone and changes across biological pathways associated with cardiovascular disease.....
2025 May 19 High temperature and ozone co-exposure induces cardiovascular damage in mice: Insights from gut microbiome and plasma metabolomics https://pubmed.ncbi.nlm.nih.gov/40393318/
..Exposure to HT and O3 leads to cardiovascular damage, which possibly implicates gut microbial dysbiosis and plasma metabolic disorder.