Re: Hello
Posted: Thu Nov 16, 2023 9:31 am
Great! I hope you do well with it. 
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Hello
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Re: Hello
Posted: Thu Nov 16, 2023 10:33 am
Thank you NHE.
Re: Hello
Posted: Thu Nov 16, 2023 3:29 pm
Did you consider Kesimpta? The self injections might be easier than getting an infusion.
Also, if you’re not taking Na-R-Lipoate then you might want to add it to your regimen. It seems to do fairly well slowing down atrophy.
Here’s a link to news about a small phase 2 study which found that lipoic acid prevented atrophy better than Ocrevus.
https://www.medicalnewstoday.com/articles/318225
Atrophy appears to be a critical factor.
Atrophy prevention Correlates with cognition.
Also, if you’re not taking Na-R-Lipoate then you might want to add it to your regimen. It seems to do fairly well slowing down atrophy.
Here’s a link to news about a small phase 2 study which found that lipoic acid prevented atrophy better than Ocrevus.
https://www.medicalnewstoday.com/articles/318225
Atrophy appears to be a critical factor.
Atrophy prevention Correlates with cognition.
Re: Hello
Posted: Fri Nov 17, 2023 12:27 am
I'm done with injections. Five years of Rebif is enough 
Lipoic acid seems promising. I just want to see some phase 3 studies.
Lipoic acid seems promising. I just want to see some phase 3 studies.
Re: Hello
Posted: Tue Nov 21, 2023 11:01 pm
I took Avonex for 10 years. A once a month injection of Kesimpta would be no big deal for me.
Dennis Bourdette’s research group at Oregon Health Science University has been studying lipoic acid in MS for roughly 20 years.
Here’s his OHSU profile.
https://www.ohsu.edu/people/dennis-bour ... -fana-faan
Here’s a link to his papers on lipoic acid.
https://pubmed.ncbi.nlm.nih.gov/?term=B ... ate&page=2
A phase 3 study is unlikely. Lipoic acid and Na-R-Lipoate are both available as OTC supplements. As such, there’s little financial resources nor incentive for conducting a large multicenter phase 3 trial.